EP-A- 1 918 302 (B9)

WO-A2-2008/118356 (B9)

EWERT S ET AL: "Stability improvement of antibodies for extracellular and intracellular applications: CDR grafting to stable frameworks and structure-based framework engineering", METHODS : A COMPANION TO METHODS IN ENZYMOLOGY, ACADEMIC PRESS INC., NEW YORK, NY, US, vol. 34, no. 2, 1 October 2004 (2004-10-01), pages 184-199, XP004526805, ISSN: 1046-2023 (B9)

FURRER ESTHER ET AL: "Pharmacokinetics and posterior segment biodistribution of ESBA105, an anti-TNF-alpha single-chain antibody, upon topical administration to the rabbit", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US, vol. 50, no. 2, 1 February 2009 (2009-02-01), pages 771-778, XP009116264, ISSN: 0146-0404 [retrieved on 2008-08-29] (B9)

HONEGGER A ET AL: "Yet Another Numbering Scheme for Immunoglobulin Variable Domains: An Automatic Modeling and Analysis Tool", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 309, no. 3, 8 June 2001 (2001-06-08), pages 657-670, XP004626893, ISSN: 0022-2836 (B9)

JUNG S ET AL: "IMPROVING IN VIVO FOLDING AND STABILITY OF A SINGLE-CHAIN FV ANTIBODY FRAGMENT BY LOOP GRAFTING", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 10, no. 8, 1 January 1997 (1997-01-01), pages 959-966, XP000971779, ISSN: 0269-2139 (B9)

KNAPPIK A ET AL: "Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 296, no. 1, 11 February 2000 (2000-02-11), pages 57-86, XP004461525, ISSN: 0022-2836 (B9)

KÜGLER MARKUS ET AL: "Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework.", PROTEIN ENGINEERING, DESIGN & SELECTION : PEDS MAR 2009, vol. 22, no. 3, March 2009 (2009-03), pages 135-147, XP002575212, ISSN: 1741-0134 (B9)

OTTIGER MICHAEL ET AL: "Efficient intraocular penetration of topical anti-TNF-alpha single-chain antibody (ESBA105) to anterior and posterior segment without penetration enhancer", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOCIATION FOR RESEARCH IN VISION AND OPHTHALMOLOGY, US, vol. 50, no. 2, 1 February 2009 (2009-02-01), pages 779-786, XP009116265, ISSN: 0146-0404 (B9)

POPKOV M ET AL: "Rabbit Immune Repertoires as Sources for Therapeutic Monoclonal Antibodies: The Impact of Kappa Allotype-correlated Variation in Cysteine Content on Antibody Libraries Selected by Phage Display", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 325, no. 2, 10 January 2003 (2003-01-10), pages 325-335, XP004457536, ISSN: 0022-2836 (B9)

RADER C ET AL: "THE RABBIT ANTIBODY REPERTOIRE AS A NOVEL SOURCE FOR THE GENERATIONOF THERAPEUTIC HUMAN ANTIBODIES", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 275, no. 18, 5 May 2000 (2000-05-05), pages 13668-13676, XP001023515, ISSN: 0021-9258, DOI: 10.1074/JBC.275.18.13668 (B9)

ROCHA R ET AL: "Rabbit monoclonal antibodies show higher sensitivity than mouse monoclonals for estrogen and progesterone receptor evaluation in breast cancer by immunohistochemistry", PATHOLOGY RESEARCH AND PRACTICE, GUSTAV FISCHER, STUTTGART, DE, vol. 204, no. 9, September 2008 (2008-09), pages 655-662, XP024098831, ISSN: 0344-0338 [retrieved on 2008-06-18] (B9)

US-A1- 2005 033 031 (B9)

US-A1- 2005 048 578 (B9)

US-A1- 2006 216 293 (B9)

WO-A-2006/131013 (B9)

WO-A-2007/001851 (B9)

WO-A-2007/047112 (B9)

WO-A-2007/124610 (B9)

WO-A-2007/140371 (B9)

WO-A-2008/004834 (B9)

WO-A-2008/006235 (B9)

WO-A2-01/30393 (B9)

WO-A2-2004/016740 (B9)

WO-A2-2005/035575 (B9)

WO-A2-2007/042775 (B9)

WO-A2-2007/042809 (B9)

EWERT S ET AL: "STRUCTURE-BASED IMPROVEMENT OF THE BIOPHYSICAL PROPERTIES OF IMMUNOGLOBULIN VH DOMAINS WITH A GENERALIZABLE APPROACH", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON, PA.; US, vol. 42, no. 6, 18 February 2003 (2003-02-18), pages 1517-1528, XP008052212, ISSN: 0006-2960 (B9)