EP-A1- 1 155 702 (B1)

YUSUKE OCHI ET AL: "A possible mechanism for the long-lasting antitumor effect of the macromolecular conjugate DE-310: mediation by cellular uptake and drug release of its active camptothecin analog DX-8951", CANCER CHEMOTHERAPY AND PHARMACOLOGY, SPRINGER, BERLIN, DE, vol. 55, no. 4, 1 April 2005 (2005-04-01), pages 323 - 332, XP019334130, ISSN: 1432-0843, DOI: 10.1007/S00280-004-0911-1 (B1)

MITSUI I ET AL: "A NEW WATER-SOLUBLE CAMPTOTHECIN DERIVATIVE, DX-8951F, EXHIBITS POTENT ANTITUMOR ACTIVITY AGAINST HUMAN TUMORS IN VITRO AND IN VIVO", JAPANESE JOURNAL OF CANCER RESE, JAPANESE CANCER ASSOCIATION, TOKYO, JP, vol. 86, no. 8, 1 August 1995 (1995-08-01), pages 776 - 782, XP009059567, ISSN: 0910-5050 (B1)

MORITZ N WENTE ET AL: "DE-310, a macromolecular prodrug of the topoisomerase-I-inhibitor exatecan (DX-8951), in patients with operable solid tumors", INVESTIGATIONAL NEW DRUGS ; THE JOURNAL OF NEW ANTICANCER AGENTS, KLUWER ACADEMIC PUBLISHERS, BO, vol. 23, no. 4, 1 August 2005 (2005-08-01), pages 339 - 347, XP019206092, ISSN: 1573-0646, DOI: 10.1007/S10637-005-1442-2 (B1)

T. M. CARDILLO ET AL: "Humanized Anti-Trop-2 IgG-SN-38 Conjugate for Effective Treatment of Diverse Epithelial Cancers: Preclinical Studies in Human Cancer Xenograft Models and Monkeys", CLINICAL CANCER RESEARCH, vol. 17, no. 10, 3 March 2011 (2011-03-03), pages 3157 - 3169, XP055044596, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-10-2939 (B1)

US-A1- 2008 131 363 (B1)

US-A1- 2011 293 513 (B1)

WO-A1-2011/068845 (B1)

WO-A1-2011/143209 (B1)

WO-A1-2014/057687 (B1)

WO-A1-2014/061277 (B1)

WO-A2-03/043583 (B1)

WO-A2-2006/065533 (B1)

WO-A2-2006/116156 (B1)

WO-A2-2007/140371 (B1)

YOSHINOBU SHIOSE ET AL: "Systematic Research of Peptide Spacers Controlling Drug Release from Macromolecular Prodrug System, Carboxymethyldextran Polyalcohol-Peptide-Drug Conjugates", BIOCONJUGATE CHEMISTRY, vol. 20, no. 1, 21 January 2009 (2009-01-21), pages 60 - 70, XP055333870, ISSN: 1043-1802, DOI: 10.1021/bc800238f (B1)

EP-A1- 2 907 824 (B1)