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Tittel COMPOSITIONS AND METHODS FOR TREATING CYTOKINE RELEASE SYNDROME
Status
Hovedstatus
Detaljstatus
Under behandling info EP under behandling Forespørsel om å gjøre EP patent gyldig er mottatt
Europeisk (EP) publiserings nummer EP4284512
EP levert
EP søknadsnummer 22704236.3
EP meddelt info
Prioritet 2021.01.28, US 202163142643 P
Sakstype Europeisk
Løpedag
Utløpsdato
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Innehaver Regeneron Pharmaceuticals, Inc. (US)
Oppfinner OLSON, Kara (US) .... se mer/flere nedenfor
Fullmektig ZACCO NORWAY AS (NO)
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Innehaver i EP:
Regeneron Pharmaceuticals, Inc.
777 Old Saw Mill River Road Tarrytown, NY 10591 US
White Plains, NY 10605 US
NY 10570 US
New York, NY 10016 US
Scarsdale, NY 10583 US
Fullmektig i Norge:
ZACCO NORWAY AS
Postboks 488 0213 OSLO NO ( OSLO kommune, Oslo fylke )

Org.nummer: 982702887
Din referanse: V491348NO00
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Kilde: Brønnøysundregistrene
Fullmektig i EP:
J A Kemp LLP
80 Turnmill Street London EC1M 5QU GB

2021.01.28, US 202163142643 P

D. W. LEE ET AL: "Current concepts in the diagnosis and management of cytokine release syndrome", BLOOD, vol. 124, no. 2, 29 May 2014 (2014-05-29), US, pages 188 - 195, XP055313556, ISSN: 0006-4971, DOI: 10.1182/blood-2014-05-552729 (B1)

XU XIAO-JUN ET AL: "Cytokine release syndrome in cancer immunotherapy with chimeric antigen receptor engineered T cells", CANCER LETTERS, NEW YORK, NY, US, vol. 343, no. 2, 16 October 2013 (2013-10-16), pages 172 - 178, XP028814569, ISSN: 0304-3835, DOI: 10.1016/J.CANLET.2013.10.004 (B1)

DANG KEVIN ET AL: "Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release", JOURNAL FOR IMMUNOTHERAPY OF CANCER, vol. 9, no. 6, 1 June 2021 (2021-06-01), pages e002488, XP55906546, Retrieved from the Internet <URL:https://jitc.bmj.com/content/9/6/e002488> DOI: 10.1136/jitc-2021-002488 (B1)

GÖKBUGET NICOLA ET AL: "Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 131, no. 14, 5 April 2018 (2018-04-05), pages 1522 - 1531, XP086510922, ISSN: 0006-4971, [retrieved on 20201104], DOI: 10.1182/BLOOD-2017-08-798322 (B1)

LI JI ET AL: "Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia", SCIENCE TRANSLATIONAL MEDICINE, vol. 11, no. 508, 4 September 2019 (2019-09-04), pages eaax8861, XP055786539, ISSN: 1946-6234, Retrieved from the Internet <URL:https://stm.sciencemag.org/content/scitransmed/11/508/eaax8861.full.pdf> DOI: 10.1126/scitranslmed.aax8861 (B1)

LI JI ET AL: "CD3 bispecific antibody-induced cytokine release is dispensable for cytotoxic T cell activity", SCIENCE TRANSLATIONAL MEDICINE, vol. 11, no. 508, 4 September 2019 (2019-09-04), pages eaax8861, XP55786539, ISSN: 1946-6234, Retrieved from the Internet <URL:https://stm.sciencemag.org/content/scitransmed/11/508/eaax8861.full.pdf> DOI: 10.1126/scitranslmed.aax8861 (B1)

LUKE JASON J ET AL: "Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors", JOURNAL FOR IMMUNOTHERAPY OF CANCER, vol. 9, no. 2, 27 April 2021 (2021-04-27), pages e002015, XP055918532, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898862/pdf/jitc-2020-002015.pdf> DOI: 10.1136/jitc-2020-002015 (B1)

SHIMABUKURO-VORNHAGEN ALEXANDER ET AL: "Cytokine release syndrome", JOURNAL FOR IMMUNOTHERAPY OF CANCER, vol. 6, no. 1, 15 June 2018 (2018-06-15), XP055918827, Retrieved from the Internet <URL:http://link.springer.com/content/pdf/10.1186/s40425-018-0343-9.pdf> DOI: 10.1186/s40425-018-0343-9 (B1)

US-A1- 2019 336 504 (B1)

WO-A1-2019/133747 (B1)

WO-A2-2017/097723 (B1)

WO-A2-2019/224718 (B1)

XIAOYING CHEN ET AL: "A Modeling Framework to Characterize Cytokine Release upon T-Cell-Engaging Bispecific Antibody Treatment: Methodology and Opportunities", CTS - CLINICAL AND TRANSLATIONAL SCIENCE, vol. 12, no. 6, 26 July 2019 (2019-07-26), US, pages 600 - 608, XP55769696, ISSN: 1752-8054, DOI: 10.1111/cts.12662 (B1)

XIAOYING CHEN ET AL: "Cytokine release syndrome in cancer immunotherapy with chimeric antigen receptor engineered T cells", CTS - CLINICAL AND TRANSLATIONAL SCIENCE, vol. 12, no. 6, 26 July 2019 (2019-07-26), US, pages 600 - 608, XP055769696, ISSN: 1752-8054, DOI: 10.1111/cts.12662 (B1)

D. W. LEE ET AL: "Current concepts in the diagnosis and management of cytokine release syndrome", BLOOD, vol. 124, no. 2, 29 May 2014 (2014-05-29), US, pages 188 - 195, XP55313556, ISSN: 0006-4971, DOI: 10.1182/blood-2014-05-552729 (B1)

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Innkommende Søknadsskjema EP (EP Form)
01-01 Søknadsskjema Patent Søknadsskjema EP (EP Form)
01-02 EP Krav V491348NO00_Claims_NO 930514
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02-01 EP Publiseringsdokument fra EPO EP Publiseringsdokument fra EPO

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