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Tittel AMINO ACID COMPOUNDS AND METHODS OF USE
Status
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Detaljstatus 		I kraft info EP patent gjort gjeldende i Norge EP patent besluttet gjeldende i Norge
Patentnummer NO/EP3761980
Europeisk (EP) publiserings nummer EP3761980
EP levert
EP søknadsnummer 19765136.7
EP meddelt
Prioritet 2018.03.07, US 201862639988 P, .... se mer/flere nedenfor
Sakstype Europeisk
Løpedag
Utløpsdato
Allment tilgjengelig
Validert i Norge
Innehaver Pliant Therapeutics, Inc. (US)
Oppfinner CHA, Jacob (US) .... se mer/flere nedenfor
Fullmektig ZACCO NORWAY AS (NO)
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Patentkrav1. Forbindelse med formel (A)eller et salt derav, hvor:R1 er C6-C14-aryl eller 5- til 10-leddet heteroaryl hvor C6-C14-arylet og det 5- til 10-leddede heteroarylet eventuelt er substituert med R1a;R2 er hydrogen; deuterium; C1-C6-alkyl eventuelt substituert med R2a; -OH; -O-C1-C6-alkyl eventuelt substituert med R2a; C3-C6-sykloalkyl eventuelt substituert med R2b; -O-C3-C6-sykloalkyl eventuelt substituert med R2b; 3- til 12-leddet heterosyklyl eventuelt substituert med R2c; eller -S(O)2R2d; med det forbehold at ethvert karbonatom bundet direkte til nitrogenatom eventuelt er substituert med en annen R2a-gruppering enn halogen;hver R1a uavhengig er C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-sykloalkyl, C4-C8-sykloalkenyl, 3- til 12-leddet heterosyklyl, 5- til 10-leddet heteroaryl, C6-C14-aryl, deuterium, halogen, -CN, -OR3, -SR3, -NR4R5, -NO2, -C=NH(OR3), -C(O)R3, -OC(O)R3, -C(O)OR3, -C(O)NR4R5, -NR3C(O)R4, -NR3C(O)OR4, -NR3C(O)NR4R5, -S(O)R3, -S(O)2R3, -NR3S(O)R4, -NR3S(O)2R4, -S(O)NR4R5, -S(O)2NR4R5 eller -P(O)(OR4)(OR5), hvor hver R1a er, hvor mulig, uavhengig eventuelt substituert med deuterium, halogen, okso, -OR6, -NR6R7, -C(O)R6, -CN, -S(O)R6, -S(O)2R6, -P(O)(OR6)(OR7), C3-C8-sykloalkyl, 3- til 12-leddet heterosyklyl, 5- til 10-leddet heteroaryl, C6-C14-aryl eller C1-C6-alkyl eventuelt substituert med deuterium, okso, -OH eller halogen;hver R2a, R2b, R2c, R2e og R2f uavhengig er okso eller R1a;R2d er C1-C6-alkyl eventuelt substituert med R2e eller C3-C5-sykloalkyl eventuelt substituert med R2f;R3 uavhengig er hydrogen, deuterium, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-sykloalkyl, C6-C14-aryl, 5- til 10-leddet heteroaryl eller 3- til 12-leddet heterosyklyl, hvor C1-C6-alkylet, C2-C6-alkenylet, C2-C6-alkynylet, C3-C6-sykloalkylet, C6-C14-arylet, det 5- til 10-leddede heteroarylet og det 3- til 12-leddede heterosyklylet til R3 uavhengig eventuelt er substituert med halogen, deuterium, okso, -CN, -OR8, -NR8R9, -P(O)(OR8)(OR9) eller C1-C6-alkyl eventuelt substituert med deuterium, halogen, -OH eller okso;hver av R4 og R5 uavhengig er hydrogen, deuterium, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-sykloalkyl, C6-C14-aryl, 5- til 6-leddet heteroaryl eller 3- til 6-leddet heterosyklyl, hvor C1-C6alkylet, C2-C6-alkenylet, C2-C6-alkynylet, C3-C6-sykloalkylet, C6-C14-arylet, det 5- til 6-leddede heteroarylet og det 3- til 6-leddede heterosyklylet til R4 og R5 uavhengig eventuelt er substituert med deuterium, halogen, okso, -CN, -OR8, -NR8R9 eller C1-C6-alkyl eventuelt substituert med deuterium, halogen, -OH eller okso;eller R4 og R5 tas sammen med det atomet de er tilknyttet for å danne et 3- til 6-leddet heterosyklyl eventuelt substituert med deuterium, halogen, okso, -OR8, -NR8R9 eller C1-C6-alkyl eventuelt substituert med deuterium, halogen, okso eller -OH;hver av R6 og R7 uavhengig er hydrogen; deuterium; C1-C6-alkyl eventuelt substituert med deuterium, halogen, eller okso; C2-C6-alkenyl eventuelt substituert med deuterium, halogen eller okso; eller C2-C6-alkynyl eventuelt substituert med deuterium, halogen eller okso;eller R6 og R7 tas sammen med det atomet de er tilknyttet for å danne et 3- til 6-leddet heterosyklyl eventuelt substituert med deuterium, halogen, okso eller C1-C6-alkyl eventuelt substituert med deuterium, halogen eller okso;hver av R8 og R9 uavhengig er hydrogen; deuterium; C1-C6-alkyl eventuelt substituert med deuterium, halogen eller okso; C2-C6-alkenyl eventuelt substituert med deuterium, halogen eller okso; eller C2-C6-alkynyl eventuelt substituert med deuterium, halogen eller okso;eller R8 og R9 tas sammen med det atomet de er tilknyttet for å danne et 3-6-leddet heterosyklyl eventuelt substituert med deuterium, halogen, okso eller C1-C6-alkyl eventuelt substituert med deuterium, okso eller halogen;hver R10, R11, R12 og R13 uavhengig er hydrogen eller deuterium;R14 er deuterium;q er 0, 1, 2, 3, 4, 5, 6, 7 eller 8;hver R15 uavhengig er valgt fra hydrogen, deuterium eller halogen;hver R16 uavhengig er valgt fra hydrogen, deuterium eller halogen; ogp er 3.2. Forbindelse ifølge krav 1, eller et salt derav, hvor:R2 er C1-C6-alkyl eventuelt substituert med R2a; C3-C6-sykloalkyl eventuelt substituert med R2b; 3- til 12-leddet heterosyklyl eventuelt substituert med R2c; eller -S(O)2R2d;R3 uavhengig er hydrogen, deuterium, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-sykloalkyl, C6-C14-aryl, 5- til 6-leddet heteroaryl eller 3- til 6-leddet heterosyklyl, hvor C1-C6-alkylet, C2-C6-alkenylet, C2-C6-alkynylet, C3-C6-sykloalkylet, C6-C14-arylet, det 5- til 6-leddede heteroarylet og det 3- til 6-leddede heterosyklylet til R3 uavhengig eventuelt er substituert med halogen, deuterium, okso, -CN, -OR8, -NR8R9, -P(O)(OR8)(OR9) eller C1-C6-alkyl eventuelt substituert med deuterium, halogen, -OH eller okso;hver R15 er hydrogen; oghver R16 er hydrogen;og hvor forbindelsen er representert ved formel (I):3. Forbindelse ifølge krav 1 eller krav 2, eller et salt derav, hvor minst én av R1a, R2a, R2b, R2c, R2e, R2f, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 eller R13 er deuterium.4. Forbindelse ifølge krav 1 eller krav 2, eller et salt derav, hvor R10, R11, R12 og R13 er hydrogen; q er 0; og hvor forbindelsen er representert ved formel (II):5. Forbindelse ifølge et hvilket som helst av kravene 1-4, eller et salt derav,hvor:R1 er 5- til 10-leddet heteroaryl eventuelt substituert med R1a;eller hvorR1 er: pyrimidinyl, kinazolinyl, pyrazolopyrimidinyl, pyrazinyl, kinolinyl, pyridopyrimidinyl, tienopyrimidinyl, pyridinyl, pyrrolopyrimidinyl, kinoksalinyl, indazolyl, benzotiazolyl, naftalenyl, purinyl eller isokinolinyl; og eventuelt er substituert med deuterium, hydroksy, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-perhaloalkyl, C1-C6-alkoksyl, C3-C8-sykloalkyl, C3-C8-halosykloalkyl, C3-C8-sykloalkoksyl, 5- til 10-leddet heteroaryl, C6-C14-aryl, cyano, amino, alkylamino eller dialkylamino;eller hvorR1 er: pyrimidin-2-yl, pyrimidin-4-yl, kinazolin-4-yl, 1H-pyrazolo[3,4-d]pyrimidin-4-yl, 1H-pyrazolo[4,3-d]pyrimidin-7-yl, pyrazin-2-yl, kinolin-4-yl, pyrido[2,3-d]pyrimidin-4-yl, pyrido[3,2-d]pyrimidin-4-yl, pyrido[3,4-d]pyrimidin-4-yl, tieno[2,3-d]pyrimidin-4-yl, tieno[3,2-d]pyrimidin-4-yl, tienopyrimidin-4-yl, pyridin-2-yl, pyridin-3-yl, 7H-pyrrolo[2,3-d]pyrimidin-4-yl, kinoksalin-2-yl, 1Hindazol-3-yl, benzo[d]tiazol-2-yl, naftalen-1-yl, 9H-purin-6-yl eller isokinolin-1-yl; og eventuelt er substituert med: ett eller flere deuterium; metyl; syklopropyl; fluor; klor; brom; difluormetyl; trifluormetyl; metyl og fluor; metyl og trifluormetyl; metoksy; cyano; dimetylamino; fenyl; pyridin-3-yl; eller pyridin-4-yl;eller hvorR1 er pyrimidin-4-yl eventuelt substituert med R1a;eller hvorR1 er pyrimidin-4-yl eventuelt substituert med R1a, hvor R1a er 5- til 10-leddet heteroaryl eller C1-C6-alkyl eventuelt substituert med halogen;eller hvorR1 er pyrimidin-4-yl eventuelt substituert med pyrazolyl, metyl, difluormetyl eller trifluormetyl;eller hvorR1 er pyrimidin-4-yl substituert med både metyl og trifluormetyl;eller hvorR1 er kinazolin-4-yl eventuelt substituert med R1a;eller hvorR1 er kinazolin-4-yl eventuelt substituert med halogen, C1-C6-alkyl eventuelt substituert med halogen eller C1-C6-alkoksy;eller hvorR1 er kinazolin-4-yl eventuelt substituert med fluor, klor, metyl, trifluormetyl eller metoksy.6. Forbindelse ifølge et hvilket som helst av kravene 1, 3, 4 eller 5, eller et salt derav, hvor R2 er:hydrogen; deuterium; hydroksy; ellerC1-C6-alkyl eller C1-C6-alkoksyl eventuelt substituert med: deuterium, halogen, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-hydroksyalkyl, C1-C6-alkoksyl, C3-C8-sykloalkyl, C3-C8-halosykloalkyl, C3-C8-sykloalkoksyl, C6-C14-aryl, C6-C14-aryloksy, 5- til 10-leddet heteroaryl, 5- til 10-leddet heteroaryloksy, 3- til 12-leddet heterosyklyl eventuelt substituert med okso, -C(O)NR4R5, -NR3C(O)R4, eller -S(O)2R3; eller hvorR2 er:metyl, metoksy, etyl, etoksy, propyl, syklopropyl eller syklobutyl;som hver eventuelt er substituert med én eller flere av: hydroksy, metoksy, etoksy, acetamid, fluor, fluoralkyl, fenoksy, dimetylamid, metylsulfonyl, syklopropoksyl, pyridin-2-yloksy, eventuelt metylert eller fluorert pyridin-3-yloksy, N-morfolinyl, N-pyrrolidin-2-onyl, dimetylpyrazol-1-yl, dioksiran-2-yl, morfolin-2-yl, oksetan-3-yl, fenyl, tetrahydrofuran-2-yl, tiazol-2-yl;som hver er substituert med 0, 1, 2 eller 3 av deuterium, hydroksy, metyl, fluor, cyano eller okso.7. Forbindelse ifølge et hvilket som helst av kravene 1-5, eller et salt derav, hvor R2 er:(i) C1-C6-alkyl eventuelt substituert med R2a;eventuelt hvor R2a er: halogen; C3-C8-sykloalkyl eventuelt substituert med halogen; 5- til 10-leddet heteroaryl eventuelt substituert med C1-C6-alkyl; - NR4R5; -NR3C(O)R4; -S(O)2R3; eller okso;eller eventuelt hvor R2a er: fluor; syklobutyl substituert med fluor; pyrazolyl substituert med metyl; eller -S(O)2CH3;(ii) C1-C6-alkyl eventuelt substituert med -OR3;eventuelt hvor R3 er: hydrogen; C1-C6-alkyl eventuelt substituert med halogen; C3-C6-sykloalkyl eventuelt substituert med halogen; C6-C14-aryl eventuelt substituert med halogen; eller 5- til 6-leddet heteroaryl eventuelt substituert med halogen eller C1-C6-alkyl;eller eventuelt hvor R3 er: hydrogen; metyl; etyl; difluormetyl; -CH2CHF2; - CH2CF3; syklopropyl substituert med fluor; fenyl eventuelt substituert med fluor; eller pyridinyl eventuelt substituert med fluor eller metyl;(iii) -CH2CH2OCH3;(iv) R2 er C1-C6-alkyl substituert med både halogen og OR3, hvor R3 er C1-C6-alkyl;.(v) R2 er C3-C6-sykloalkyl eventuelt substituert med R2b; eller(vi) R2 er syklopropyl.8. Forbindelse ifølge et hvilket som helst av kravene 1-4, eller et salt derav, hvor(a) R1 er hvor m er 0, 1, 2 eller 3 og hver R1a, der det er aktuelt, uavhengig er deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium; hvor hver R1a uavhengig er deuterium, alkyl, haloalkyl eller heteroaryl; hvor m er 0, 1, 2 eller 3 og hver R1a, der det er aktuelt, uavhengiger deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium;(d) R1 er hvor m er 0, 1, 2, 3, 4 eller 5 og hver R1a, der det er aktuelt, uavhengig er deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium; r R1a uavhengiger deuterium, halogen, alkyl, haloalkyl eller alkoksy;hvor m er 0, 1, 2, 3, 4 eller 5 og hver R1a, der det er aktuelt, uavhengig er deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium;(f) R1 er hvor m er 0, 1, 2, 3 eller 4, og hver R1a, der det er aktuelt, uavhengig er deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium; eventuelt hvor R1 er valgt fra gruppen bestående av hvor m er 0, 1, 2, 3 eller 4, og hver R1a, der det er aktuelt, uavhengig erdeuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium; eventuelt hvor R1 er valgt fra gruppen bestående av(h) R1 er hvor m er 0, 1, 2, 3 eller 4, og hver R1a, der det er aktuelt, uavhengig er deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium; eventuelt hvor R1 er valgt fra gruppen bestående av(i) R1 er hvor m er 0, 1, 2, 3, 4, 5 eller 6 og hver R1a, der det er aktuelt, uavhengig er deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium; hvor m er 0, 1, 2, 3, 4, 5 eller 6 og hver R1a, der det er aktuelt, uavhengiger deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium; hvor m er 0, 1 eller 2 og hver R1a, der det er aktuelt, uavhengig er deuterium, halogen, alkyl, haloalkyl, alkoksy, hydroksy, -CN, eller heteroaryl, hvor alkylet, haloalkylet, alkoksyet, hydroksyen og heteroarylet til R1a uavhengig eventuelt er substituert med deuterium;(l) R1 er valgt fra gruppen beståendeog hvilke som helst av de foregående grupper hvor ett eller flere vilkårlig(e) hydrogenatom(er) er erstattet med deuteriumatom(er);(m) R1 er valgt fra gruppen beståendeog hvilke som helst av de foregående grupper hvor ett eller flere vilkårlig(e) hydrogenatom(er) er erstattet med deuteriumatom(er);(n) R1 er valgt fra gruppen bestående avog hvilke som helst av de foregående grupper hvor ett eller flere vilkårlig(e) hydrogenatom(er) er erstattet med deuteriumatom(er); eller (o) R1 er valgt fra gruppen bestående aog hvilke som helst av de foregående grupper hvor ett eller flere vilkårlig(e) hydrogenatom(er) er erstattet med deuteriumatom(er).9. Forbindelse ifølge et hvilket som helst av kravene 1 til 5 eller 8, eller et salt derav, hvor R2 er hvor n er 1, 2, 3, 4, 5 eller 6, og R3 er C1-C2-alkyl eventuelt substituert med fluor; fenyl eventuelt substituert med fluor; pyridinyl eventuelt substituert med fluor eller metyl; eller syklopropyl eventuelt substituert med fluor;eller hvor R2 er valgt fra gruppen beståendeog hvilke som helst av de foregående grupper hvor ett eller flere vilkårlig(e) hydrogenatom(er) er erstattet med deuteriumatom(er);eller hvor R2 er valgt fra gruppen bestående aog hvilke som helst av de foregående grupper hvor ett eller flere vilkårlig(e) hydrogenatom(er) er erstattet med deuteriumatom(er);eller hvor R2 er C1-C6-alkyl eventuelt substituert med -OR3, og R3 er fenyl eventuelt substituert med fluor;eller hvor R2 er C1-C6-alkyl eventuelt substituert med -OR3, hvor R3 er pyridinyl eventuelt substituert med fluor eller metyl;eller hvor R2 er C1-C6-alkyl substituert med R2a, hvor R2a er halogen; eller(ii) C1-C6-alkyl substituert med R2a, hvor R2a er deuterium; eller(iii) C1-C6-alkyl substituert med R2a, hvor R2a er 3- til 12-leddet heterosyklyl eventuelt substituert med okso; eller(iv) C1-C6-alkyl substituert med R2a, hvor R2a er 4- til 5-leddet heterosyklyl eventuelt substituert med okso; eller (v) C1-C6-alkyl substituert med R2a, hvor R2a er C6-C14-aryl eventuelt substituert med halogen eller -OR6; eller(vi) C1-C6-alkyl substituert med R2a, hvor R2a er fenyl eventuelt substituert med halogen eller -OR6; eller(vii) C1-C6-alkyl substituert med R2a, hvor R2a er 5- til 10-leddet heteroaryl eventuelt substituert med C1-C6-alkyl; eller(viii) C1-C6-alkyl substituert med R2a, hvor R2a er pyrazolyl eventuelt substituert med metyl; eller (ix) C1-C6-alkyl substituert med R2a, hvor R2a er C3-C8-sykloalkyl eventuelt substituert med -CN, halogen eller -OR6; eller(x) C1-C6-alkyl substituert med R2a, hvor R2a er -S(O)2R3.10. Forbindelse ifølge et hvilket som helst av kravene 1-4, eller et salt derav,hvor R1 er pyridyl eventuelt substituert med R1a; ellerhvor R1 er indazolyl eventuelt substituert med R1a; ellerhvor R1 er 1H-pyrrolopyridyl eventuelt substituert med R1a; ellerhvor R1 er kinolinyl eventuelt substituert med R1a; ellerhvor R1 er fenyl eventuelt substituert med R1a; ellerhvor R1 er indanyl eventuelt substituert med R1a.11. Forbindelse ifølge krav 1, eller et salt derav, valgt fra gruppen bestående av(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(difluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-hydroksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((7-fluorkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metylkinazolin-4-yl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[2,3-d]pyrimidin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-(trifluormetyl)kinazolin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)kinazolin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((8-(trifluormetyl)kinazolin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,4-d]pyrimidin-4-ylamino)smørsyre;(S)-2-((5-fluorkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-fluorkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((8-fluorkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6,7-difluorkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(difluormetyl)pyrimidin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre; (S)-4-(((S)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl)amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((3,3-difluorsyklobutyl)metyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-fluor-2-metylkinazolin-4-yl) amino)smørsyre;(S)-2-(isokinolin-1-ylamino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;.(S)-4-((2-(difluormetoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinolin-4-ylamino)smørsyre;(S)-2-((7-klorkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((8-klorkinazolin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-(kinazolin-4-ylamino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metoksykinazolin-4-yl) amino)smørsyre; (2S)-4-((2-(2,2-difluorsyklopropoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-fluor-2-metylkinazolin-4-yl) amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((8-metoksykinazolin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metylkinazolin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((8-klorkinazolin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl)oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl)oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre; (S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;.(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metylkinazolin-4-yl) amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-hydroksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre; (S)-2-((3-cyanopyrazin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-fluorpyrimidin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre; (S)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre; (S)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre; (S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fluorpyrimidin-2-yl) amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl)amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(2S)-4-((oksetan-2-ylmetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((3-hydroksy-2-(hydroksymetyl)propyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl) pyrimidin-2-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((3-fluoroksetan-3-yl) metyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-syklopropylpyrimidin-2-yl) amino)smørsyre;4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-2-ylamino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;2-((5-cyanopyrimidin-2-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-brompyrimidin-2-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre; (S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fluorpyrimidin-2-yl) amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naphthyridi n-2-yl) butyl)amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3,3-difluorsyklobutyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre; (S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((5-metylpyrimidin-2-yl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;2-((5-cyanopyrimidin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-brompyrimidin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metylpyrazin-2-yl) amino)smørsyre;2-((3-cyanopyrazin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;2-((5-fluorpyrimidin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)smørsyre;(R)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-syklopropylpyrimidin-2-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(dimetylamino)pyrimidin-4-yl)amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metoksypyrazin-2-yl) amino)smørsyre;4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) amino)-2-((6-fenylpyrazin-2-yl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazol-5-yl) amino)smørsyre;(S)-2-(benzo[d]oxazol-2-ylamino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-2-((9H-purin-6-yl)amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indazol-3-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indol-3-yl) amino)smørsyre;2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-brompyrimidin-2-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-(metylsulfonyl)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre; (S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-brompyrimidin-2-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;2-((5-syklopropylpyrimidin-2-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre; (S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl) amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidi n-4-yl) amino)smørsyre;(S)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidi n-4-yl) amino)smørsyre;4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;2-((5-cyanopyrimidin-2-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-brompyrimidin-2-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; 2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((3-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-cyanopyrimidin-2-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-brompyrimidin-2-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; 2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((5-brompyrimidin-2-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre; (S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-etoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-(((S)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl)amino)smørsyre; (S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-cyanopyrimidin-2-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-brompyrimidin-2-yl) amino)smørsyre;(S)-2-((7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-syklopropylpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(tertbutyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((3-cyanopyrazin-2-yl) amino)smørsyre; (S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-2-([4,4'-bipyridin]-2-ylamino)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fluorpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre; (S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metylpyrazin-2-yl) amino)smørsyre;2-((3-cyanopyrazin-2-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((5-fluorpyrimidin-2-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metoksypyrazin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazol-5-yl) amino)smørsyre; (S)-2-(benzo[d]oxazol-2-ylamino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-2-((9H-purin-6-yl) amino)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indazol-3-yl) amino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indol-3-yl) amino)smørsyre;(R)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((2-metoksypyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-metylpyrazin-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((5-fluorpyrimidin-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-2-((5-metoksypyrazin-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre; (S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-2-((9H-purin-6-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-(benzo[d]oxazol-2-ylamino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-pyrazol-5-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-indazol-3-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-indol-3-yl) amino)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl) amino)smørsyre; (S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fluorpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre; (S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metoksypyrazin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-2-((9H-purin-6-yl) amino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)smørsyre;(S)-2-(benzo[d]oxazol-2-ylamino)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazol-5-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indazol-3-yl) amino)smørsyre;(S)-4-((2-((5-fluorpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indol-3-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((2-metoksypyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-metylpyrazin-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((5-fluorpyrimidin-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-2-((5-metoksypyrazin-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre; (S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-2-((1-metyl-1H-pyrazol-5-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-(benzo[d]oxazol-2-ylamino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((9H-purin-6-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-((2-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-2-((1-metyl-1H-indazol-3-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-indol-3-yl) amino)-4-((2-((6-metylpyridin-3-yl) oksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-metylpyrimidin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-(pyridin-2-ylamino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((2-metoksypyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-metylpyrazin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-2-((5-fluorpyrimidin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-2-((5-metoksypyrazin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-fenylpyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-2-((2-fenylpyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-fenylpyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-2-((5-fenylpyrazin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-fenylpyrazin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-pyrazol-5-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-(benzo[d]oxazol-2-ylamino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((9H-purin-6-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-fenylpyridin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((4-fenylpyridin-2-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-indol-3-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1-metyl-1H-indazol-3-yl) amino)-4-((2-(pyridin-2-yloksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metylpyrazin-2-yl) amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fluorpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metoksypyrazin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazol-5-yl) amino)smørsyre;(S)-2-(benzo[d]oxazol-2-ylamino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-2-((9H-purin-6-yl) amino)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indazol-3-yl) amino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indol-3-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metylpyrazin-2-yl) amino)smørsyre; (S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fluorpyrimidin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metoksypyrazin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyl-2-(pyridin-4-yl) pyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-(pyridin-4-yl) pyrazin-2-yl) amino)smørsyre; (S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazol-5-yl) amino)smørsyre;(S)-2-(benzo[d]oxazol-2-ylamino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-benzo[d]imidazol-2-yl) amino)smørsyre;(S)-2-(benzo[d]tiazol-2-ylamino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-2-((9H-purin-6-yl) amino)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indazol-3-yl) amino)smørsyre;(S)-4-((2-(3,5-dimetyl-1H-pyrazol-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indol-3-yl) amino)smørsyre;(R)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (5-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) pentyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(2S)-2-(kinazolin-4-ylamino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) ((tetrahydrofuran-2-yl) metyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre; (S)-4-((3,3-difluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(R)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(R)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-((2,2-difluor-4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-metoksyetyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2,2-difluoretyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-2-ylamino)smørsyre;(S)-4-((2-(dimetylamino)-2-oksoetyl)(4-(5, 6,7, 8-tetrahydro-1, 8-naphthyri din-2-yl)butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl)amino)smørsyre;.(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl) amino)smørsyre;(S)-4-((2-fluor-3-hydroksy-2-(hydroksymetyl)propyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((3-hydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(R)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((2-(2-oksopyrrolidin-1-yl) etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-(syklopropyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(benzo[d]tiazol-2-ylamino)smørsyre; (S)-2-((1-metyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrimidin-4-ylamino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metoksypyrimidin-4-yl) amino)smørsyre;(S)-2-((6-(dimetylamino)pyrimidin-4-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((6-(tert-butyl)pyrimidin-4-yl) amino)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-fenylpyrimidin-4-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fenylpyrazin-2-yl) amino)smørsyre;(S)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)-2-((5-(trifluormetyl)pyrimidin-2-yl) amino)smørsyre;(S)-2-((5-cyanopyrimidin-2-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((5-brompyrimidin-2-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre; (S)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)-2-((2-(trifluormetyl)pyrimidin-4-yl) amino)smørsyre;(S)-2-((5-syklopropylpyrimidin-2-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((2-(pyridin-3-yl) kinazolin-4-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((6-fenylpyrimidin-4-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((5-fenylpyrimidin-4-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-(pyrimidin-4-ylamino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-2-((6-(1H-pyrazol-1-yl) pyrimidin-4-yl) amino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (2-(2,2,2-trifluoretoksy)etyl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metylpyrimidin-2-yl) amino)smørsyre;(S)-2-((3-cyanopyrazin-2-yl) amino)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-([4,4'-bipyridin]-2-ylamino)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((4-fenylpyridin-2-yl) amino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((5-fenylpyridin-2-yl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((6-metylpyrazin-2-yl)amino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinoksalin-2-ylamino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((6-metyl-2-(pyridin-4-yl)pyrimidin-4-yl)amino)smørsyre; (S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((1-metyl-1H-indazol-3-yl) amino)smørsyre;(S)-4-((2-acetamidoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(benzo[d]tiazol-2-ylamino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyridin-3-ylamino)smørsyre;(S)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(naftalen-1 -ylamino)smørsyre;(S)-4-((2-morfolinoetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(2S)-4-((2,3-dihydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;4-((2-metoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(naftalen-1-ylamino)smørsyre;(2S)-4-((3-fluor-2-hydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-(kinazolin-4-ylamino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl) (tiazol-2-ylmetyl)amino)smørsyre;(S)-4-((2-(3-oksomorfolino)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(benzyl(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((R)-2-hydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(2S)-4-(((1,4-dioxan-2-yl) metyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((S)-3-fluor-2-hydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((S)-2-hydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(2S)-4-((morfolin-3-ylmetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(2S)-4-((3,3-difluor-2-hydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre; (S)-4-(((S)-2,3-dihydroksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-hydroksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[2,3-d]pyrimidin-4-ylamino)smørsyre;(S)-4-((2-hydroksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-((2-hydroksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-((2-hydroksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((S)-2-fluor-3-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-4-(metoksy(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-metoksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl) amino)-4-((2-metoksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((3-hydroksyoksetan-3-yl) metyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-metoksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[2,3-d]pyrimidin-4-ylamino)smørsyre;(S)-4-((2-metoksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(pyrido[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-4-((2-metoksy-2-metylpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metylkinazolin-4-yl) amino)smørsyre;(S)-4-(((1-cyanosyklopropyl)metyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((2-metylkinazolin-4-yl) amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-fluor-2-metylkinazolin-4-yl) amino)smørsyre; (S)-2-(kinazolin-4-ylamino)-4-((4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((8-fluorkinazolin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((7-fluorkinazolin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((8-metylkinazolin-4-yl) amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metylkinazolin-4-yl) amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-fluorkinazolin-4-yl) amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((8-metylkinazolin-4-yl) amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((8-fluorkinazolin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metylkinazolin-4-yl) amino)smørsyre;(S)-2-((6-fluorkinazolin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-fluorkinazolin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(tieno[2,3-d]pyrimidin-4-ylamino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(tieno[2,3-d]pyrimidin-4-ylamino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyltieno[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyltieno[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(tieno[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyltieno[3,2-d]pyrimidin-4-yl) amino)smørsyre; (S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-(tieno[3,2-d]pyrimidin-4-ylamino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((6-metyltieno[3,2-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metyltieno[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((5-metyltieno[2,3-d]pyrimidin-4-yl) amino)smørsyre;(S)-2-((7,8-difluorkinazolin-4-yl) amino)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-2-((7,8-difluorkinazolin-4-yl) amino)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyltieno[3,2-d]pyrimidin-4-yl) amino)smørsyre; og(S)-4-(((R)-2-metoksypropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-2-((7-metyltieno[3,2-d]pyrimidin-4-yl) amino)smørsyre.12. Forbindelse ifølge krav 1, eller et salt derav, hvor forbindelsen har formelenhvor m er 0, 1, 2, 3, 4 eller 5.13. Forbindelse ifølge krav 1, hvor forbindelsen er valgt fra:(S)-2-((7-fluorkinazolin-4-yl)amino)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl)amino)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre; (S)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((8-(trifluormetyl)kinazolin-4-yl)amino)smørsyre;(S)-2-((6-fluorkinazolin-4-yl)amino)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre;(S)-2-((6,7-difluorkinazolin-4-yl)amino)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre;(S)-2-((7-fluor-2-metylkinazolin-4-yl)amino)-4-((2-(4-fluorfenoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre;(2S)-4-((2-(2,2-difluorsyklopropoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((7-fluor-2-metylkinazolin-4-yl)amino)smørsyre;(S)-4-(((S)-3-fluor-2-metoksypropyl)(4-(5, 6,7, 8-tetrahydro-1, 8-naphthyri din-2-yl)butyl)amino)-2-((2-metylkinazolin-4-yl)amino)smørsyre;(S)-2-((8-fluorkinazolin-4-yl)amino)-4-(((R)-2-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre;(S)-2-((7-fluorkinazolin-4-yl)amino)-4-(((R)-2-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre;(S)-4-(((R)-2-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((8-metylkinazolin-4-yl)amino)smørsyre;(S)-2-((7,8-difluorkinazolin-4-yl)amino)-4-(((R)-2-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre;(S)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-fenoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-(3,5-difluorfenoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-(pyridin-2-yloksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-(2,2-difluoretoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-((2-((6-metylpyridin-3-yl)oksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((R)-2-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre; (S)-4-((2-hydroksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre;(S)-4-(((R)-2-hydroksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre; og(S)-4-(((S)-2,3-dihydroksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre,eller et salt derav.14. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-2-((7-fluor-2-metylkinazolin-4-yl)amino)-4-((2-(4-fluorfenoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre, eller et salt derav.15. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-4-((2-hydroksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre, eller et salt derav.16. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-4-((2-metoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre, eller et salt derav.17. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-4-((2-(3,5-difluorfenoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(kinazolin-4-ylamino)smørsyre, eller et salt derav.18. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-4-((2-fenoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((5-fenylpyrimidin-4-yl)amino)smørsyre, eller et salt derav.19. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-4-((2-(4-fluorfenoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((5-fenylpyrimidin-4-yl)amino)smørsyre, eller et salt derav.20. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-2-((6-(1H-pyrazol-1-yl)pyrimidin-4-yl)amino)-4-((3-fluorpropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre, eller et salt derav.21. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-4-(((S)-3-fluor-2-metoksypropyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-(tieno[2,3-d]pyrimidin-4-ylamino)smørsyre, eller et salt derav.22. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl)amino)-4-((2-fenoksyetyl)(4-(5, 6,7, 8-tetrahydro-1, 8-naftyridin-2-yl)butyl)amino)smørsyre, eller et salt derav.23. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)-4-((2-fenoksyetyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre, eller et salt derav.24. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-2-((1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)-4-((2-(4-fluorfenoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)smørsyre, eller et salt derav.25. Forbindelse ifølge krav 1, hvor forbindelsen er (S)-4-((2-(4-fluorfenoksy)etyl)(4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butyl)amino)-2-((2-metyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl)amino)smørsyre, eller et salt derav.26. Farmasøytisk sammensetning omfattende en forbindelse ifølge et hvilket som helst av kravene 1 til 25, eller et farmasøytisk akseptabelt salt derav, og en farmasøytisk akseptabel bærer eller tilsetning.27. Forbindelse ifølge et hvilket som helst av kravene 1 til 25 eller et farmasøytisk akseptabelt salt derav, eller farmasøytisk sammensetning ifølge krav 26, for bruk ved behandling av en fibrotisk sykdom.28. Forbindelse eller farmasøytisk akseptabelt salt derav eller farmasøytisk sammensetning for bruk ifølge krav 27, hvor den fibrotiske sykdommen er lungefibrose, leverfibrose, hudfibrose, hjertefibrose, nyrefibrose, gastrointestinal fibrose, primær skleroserende kolangitt eller biliær fibrose.29. Forbindelse ifølge et hvilket som helst av kravene 1 til 25, eller et farmasøytisk akseptabelt salt derav, for bruk ved behandling av idiopatisk lungefibrose. 30. Forbindelse ifølge et hvilket som helst av kravene 1 til 25, eller et farmasøytisk akseptabelt salt derav, for bruk ved behandling av primær skleroserende kolangitt.31. Forbindelse, hvor forbindelsen er:(a) N-(2-(4-fluorfenoksy)etyl)-4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butanamideller et salt derav;(b) en forbindelse med formel 3A:hvor R2 er 2-hydroksyetyl eller 2-metoksyetyl;eller et salt derav;(c) en forbindelse med formel 2C:hvor R er 3,5-difluorfenoksymetyl;eller et salt derav;(d) N-(2-fenoksyetyl)-4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butanamideller et salt derav; eller (e) N-(2-(4-fluorfenoksy)etyl)-4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butanamideller et salt derav.32. Forbindelse, hvor forbindelsen er:(a) en forbindelse med formel 3C:hvor R er 4-fluorfenoksymetyl eller 3,5-difluorfenoksymetyl;eller et salt derav;(b) en forbindelse med formel 4A:hvor R2 er 2-hydroksyetyl eller 2-metoksyetyl;eller et salt derav;(c) N-(2-fenoksyetyl)-4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butan-1-amineller et salt derav;(d) N-(2-(4-fluorfenoksy)etyl)-4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl)butan-1-amin eller et salt derav;(e) tert-butyl 7-(4-((3-fluorpropyl)amino)butyl)-3,4-dihydro-1,8-naftyridin-1(2H)-karboksylateller et salt derav; eller(f) tert-butyl (S)-7-(4-((3-fluor-2-metoksypropyl)amino)butyl)-3,4-dihydro-1,8-naftyridin-1(2H)-karboksylateller et salt derav.33. Forbindelse, hvor forbindelsen er:(a) en forbindelse med formel 9C:hvor:(i) R1 er 7-fluor-2-metylkinazolin-4-yl og R er 4-fluorfenoksymetyl, eller(ii) R1 er kinazolin-4-yl og R er 3,5-difluorfenoksymetyl;eller et salt derav;(b) en forbindelse med formel 10A: hvor:(i) R1 er kinazolin-4-yl og R2 er 2-hydroksyetyl,(ii) R1 er kinazolin-4-yl og R2 er 2-metoksyetyl, eller(iii) R1 er tieno[2,3-d]pyrimidin-4-yl og R2 er (S)-3-fluor-2-metoksypropyl; eller et salt derav.34. Forbindelse, hvor forbindelsen er:(a) en forbindelse med formel 5D:hvor R er 4-fluorfenoksymetyl;eller et salt derav;(b) en forbindelse med formel 6A:hvor:(i) R2 er hydroksyetyl, eller(ii) R2 er metoksyetyl;eller et salt derav;(c) en forbindelse med formel 5C: hvor R er 3,5-difluorfenoksymetyl;eller et salt derav;(d) metyl (S)-2-(((benzyloksy)karbonyl)amino)-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-butanoateller et salt derav;(e) (S)-metyl 2-(((benzyloksy)karbonyl)amino)-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-butanoat; eller et salt derav;(f) (S)-metyl 2-(((benzyloksy)karbonyl)amino)-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)-butanoateller et salt derav; eller(g) en forbindelse med formel 7B:hvor R2 er (S)-3-fluor-2-metoksypropyl;eller et salt derav.35. Forbindelse, hvor forbindelsen er:(a) en forbindelse med formel 6C: hvor:(i) R er 4-fluorfenoksymetyl, eller(ii) R er 3,5-difluorfenoksymetyl;eller et salt derav;(b) en forbindelse med formel 7A:hvor:(i) R2 er 2-hydroksyetyl,(ii) R2 er 2-metoksyetyl, eller(iii) R2 er (S)-3-fluor-2-metoksypropyl;eller et salt derav(c) (S)-2-amino-4-((2-fenoksyetyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyreeller et salt derav;(d) (S)-2-amino-4-((2-(4-fluorfenoksy)etyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyre eller et salt derav; eller(e) (S)-2-amino-4-((3-fluorpropyl) (4-(5,6,7,8-tetrahydro-1,8-naftyridin-2-yl) butyl)amino)smørsyreeller et salt derav.
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Innehaver(e) info chevron_right

Innehaver i EP:
Pliant Therapeutics, Inc.
260 Littlefield Avenue South San Francisco, CA 94080 US

Oppfinner(e) info chevron_right

CHA, Jacob
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
DONG, Chengguo
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
HOM, Timothy
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
JIANG, Lan
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
LEFTHERIS, Katerina
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
LI, Hui
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
MORGANS JR., David J.
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
MUNOZ, Manuel
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
REILLY, Maureen
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
ZHENG, Yajun
c/o Pliant Therapeutics, Inc. 260 Littlefield Avenue South San Francisco, California 94080 US
BAILEY, Christopher
South San Francisco, California 94080 US
FINKELSTEIN, Darren
South San Francisco, California 94080 US

Fullmektig info chevron_right

Fullmektig i Norge:
ZACCO NORWAY AS
Postboks 488 0213 OSLO NO ( OSLO kommune, Oslo fylke )

Org.nummer: 982702887
Din referanse: V470341NO00
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Kilde: Brønnøysundregistrene
Fullmektig i EP:
Mewburn Ellis LLP
Aurora Building Counterslip Bristol BS1 6BX GB

Prioritet info chevron_right

2018.03.07, US 201862639988 P

2018.06.27, US 201862690933 P

Anførte dokumenter info chevron_right

WO-A1-2018/009501 (B1)

US-A1- 2002 010 176 (B1)

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Utgående EP Registreringsbrev (3210) (PTEP3761980)
03-01 Brev UT EP Registreringsbrev (3210) (PTEP3761980)
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01-01 Søknadsskjema Patent Søknadsskjema Patent
01-02 Fullmakt V470341NO00_POA
01-03 EP Krav V470341NO00-Claims NO
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Til betaling:

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Årsavgift 7. avg. år (EP) 2025.03.12 2860 CPA GLOBAL LIMITED Betalt og godkjent
Årsavgift 6. avg. år (EP) 2024.02.23 2000 Daniel Banczer Betalt og godkjent
32401351 expand_more 2024.01.30 5500 ZACCO NORWAY AS Betalt
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Hva betyr A1, B, B1, C osv? info
Kapitler uten data er fjernet. Melding opprettet: 25.04.2025 07:06:59