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2016.07.11, US 201662360876 P
2016.07.11, US 201662360884 P
2016.07.11, US 201662360887 P
BARBORA SLAV?KOV? ET AL: "Allopregnanolone and Pregnanolone Analogues Modified in the C Ring: Synthesis and Activity", JOURNAL OF MEDICINAL CHEMISTRY, vol. 56, no. 6, 28 March 2013 (2013-03-28), US, pages 2323 - 2336, XP055406860, ISSN: 0022-2623, DOI: 10.1021/jm3016365 (B1)
ZENG C-M ET AL: "Neurosteroid Analogues. 10. The Effect of Methyl Group Substitution at the C-6 and C-7 Positions on the GABA Modulatory and Anesthetic Actions of (3alpha,5alpha))- and (3alpha,5beta)-3-Hydroxypregnan-20-one", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 48, no. 8, 25 March 2005 (2005-03-25), pages 3051 - 3059, XP003021562, ISSN: 0022-2623, DOI: 10.1021/JM049027+ (B1)
CRISTINA SUÑOL ET AL: "Activity of B-Nor Analogues of Neurosteroids on the GABA A Receptor in Primary Neuronal Cultures", JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, no. 11, 1 June 2006 (2006-06-01), US, pages 3225 - 3234, XP055570705, ISSN: 0022-2623, DOI: 10.1021/jm060002f (B1)
HANA CHODOUNSKÁ ET AL: "Epalons: Synthesis of 3[alpha],7[alpha]-Dihydroxy-5[alpha]-pregnan-20-one", COLLECTION SYMPOSIUM SERIES (XIIITH SYMPOSIUM ON CHEMISTRY OF NUCLEIC ACID COMPONENTS SPINDLERUV MLYN, CZECH REPUBLIC; SEPTEMBER 03 -09, 2005), vol. 63, no. 10, 1998, XX, pages 1543 - 1548, XP055406876, ISSN: 0010-0765, ISBN: 978-80-86241-25-8, DOI: 10.1135/cccc19981543 (B1)
JUNGMANN R ET AL: "7-Keto-5-[beta]-ätiansäure-Derivate. Über Gallensäuren und verwandte Stoffe, 51. Mitteilung [Bile acids and related substances. LI. 7-Oxo-5.beta.-etianic acid derivatives]", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA, CH, vol. 41, no. 5, 1958, pages 1206 - 1233, XP009500207, ISSN: 0018-019X, [retrieved on 20041024], DOI: 10.1002/HLCA.19580410507 (B1)
KRAFFT ET AL: "Synthesis of the C/D/E and A/B Rings of Xestobergsterol-(A)", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY ETC.|, vol. 64, no. 7, 18 March 1999 (1999-03-18), pages 2475 - 2485, XP002216916, ISSN: 0022-3263, DOI: 10.1021/JO982319W (B1)
LEHMANN G ET AL: "Schweinegallensauren. V. Der Abbau von Hyocholsaure zu Pregnanderivaten. [Swine bile acids. V. Degradation of hyocholic acid into pregnanone derivatives]", JOURNAL FÜR PRAKTISCHE CHEMIE : PRACTICAL APPLICATIONS AND APPLIED CHEMISTRY : COVERING ALL ASPECTS OF APPLIED CHEMISTRY, WILEY, DE, vol. 32, no. 3-4, 1 July 1966 (1966-07-01), pages 217 - 224, XP009500206, ISSN: 0021-8383, [retrieved on 20041108], DOI: 10.1002/PRAC.19660320316 (B1)
MONICA E DELUCA ET AL: "98. Synthesis of 3P-Hydro~y[Zl-'~C]-5/?-pregn-8( 14)-en-20-one from Chenodeoxycholic Acid", 1986, XP055407089, Retrieved from the Internet <URL:http://onlinelibrary.wiley.com/store/10.1002/hlca.19860690810/asset/19860690810_ftp.pdf?v=1&t=j7lpx7ms&s=1fe8c4e128f3e83679125527ed5551f9d1640064> (B1)
PATRICE C PEART ET AL: "Hydroxylation of steroids by,and", STEROIDS, ELSEVIER SCIENCE PUBLISHERS, NEW YORK, NY, US, vol. 76, no. 12, 7 July 2011 (2011-07-07), pages 1317 - 1330, XP028286807, ISSN: 0039-128X, [retrieved on 20110707], DOI: 10.1016/J.STEROIDS.2011.06.010 (B1)
PURDY R H ET AL: "Synthesis, Metabolism, and Pharmacological Activity of 3.alpha.-Hydroxy Steroids Which Potentiate GABA-Receptor-Mediated Chloride Ion Uptake in Rat Cerebral Cortical Synaptoneurosomes", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 33, no. 6, 1 January 1990 (1990-01-01), pages 1572 - 1581, XP002012635, ISSN: 0022-2623, DOI: 10.1021/JM00168A008 (B1)
SLAVIKOVA BARBORA ET AL: "3.ALPHA.-FLUORO ANALOGUES OF ALLOPREGNANOLONE AND THEIR BINDING TO GABAARECEPTORS", COLLECTION SYMPOSIUM SERIES (XIIITH SYMPOSIUM ON CHEMISTRY OF NUCLEIC ACID COMPONENTS SPINDLERUV MLYN, CZECH REPUBLIC; SEPTEMBER 03 -09, 2005); [COLLECTION SYMPOSIUM SERIES / INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY, ACADEMY OF SCIENCES OF THE, vol. 67, no. 1, 1 January 2002 (2002-01-01), pages 30 - 46, XP008073174, ISSN: 0010-0765, ISBN: 978-80-86241-25-8, DOI: 10.1135/CCCC20020030 (B1)
STASTNA E ET AL: "Synthesis of C3, C5, and C7 pregnane derivatives and their effect on NMDA receptor responses in cultured rat hippocampal neurons", STEROIDS, ELSEVIER SCIENCE PUBLISHERS, NEW YORK, NY, US, vol. 74, no. 2, 24 November 2008 (2008-11-24), pages 256 - 263, XP025894826, ISSN: 0039-128X, [retrieved on 20081124], DOI: 10.1016/J.STEROIDS.2008.11.011 (B1)
US-A1- 2016 108 080 (B1)
WO-A1-2015/180679 (B1)
WO-A1-98/05337 (B1)
WO-A2-2010/003391 (B1)
BARBORA SLAVÍKOVÁ ET AL: "Allopregnanolone (3[alpha]-Hydroxy-5[alpha]-pregnan-20-one) Derivatives with a Polar Chain in Position 16[alpha]: Synthesis and Activity", JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, no. 7, 9 April 2009 (2009-04-09), pages 2119 - 2125, XP055406982, ISSN: 0022-2623, DOI: 10.1021/jm801454a (B1)
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Utgående
EP Registreringsbrev (3210) (PTEP3481844)
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Innkommende, AR625325020
Søknadsskjema Patent
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Betalingshistorikk:
Beskrivelse / Fakturanummer | Betalingsdato | Beløp | Betaler | Status |
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Årsavgift 8. avg. år (EP) | 2024.07.29 | 3320 | CLARIVATE IP SERVICES LIMITED | Betalt og godkjent |
32409454 expand_more expand_less | 2024.07.17 | 7254 | PLOUGMANN VINGTOFT NUF | Betalt |
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