"BIOLOGY OF MICROORGANISMS ON GRAPES IN MUST AND IN WINE", 1 January 2009, article HELMUT KONIG ET AL: "BIOLOGY OF MICROORGANISMS ON GRAPES IN MUST AND IN WINE (PASSAGE)", pages: 175 - 177, XP055750943 (B1)

ZOLODZ M D ET AL: "Separation by hydrophobic interaction chromatography and structural determination by mass spectrometry of mannosylated glycoforms of a recombinant transferrin-exendin-4 fusion protein from yeast", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER, AMSTERDAM, NL, vol. 1217, no. 2, 8 January 2010 (2010-01-08), pages 225 - 234, XP026817105, ISSN: 0021-9673, [retrieved on 20091030] (B1)

ANONYMOUS: "EasySelect (TM) Pichia Expression Kit", 18 June 2010 (2010-06-18), pages I-VIII - 1-87, XP055015858, Retrieved from the Internet <URL:http://tools.invitrogen.com/content/sfs/manuals/easyselect_man.pdf> [retrieved on 20120106] (B1)

ANONYMOUS: "Pichia Fermentation Process Guidelines", 30 May 2002 (2002-05-30), pages 1 - 11, XP055015860, Retrieved from the Internet <URL:http://tools.invitrogen.com/content/sfs/manuals/pichiaferm_prot.pdf> [retrieved on 20120106] (B1)

ANONYMOUS: "The Gold Sheet", PHARMACEUTICAL & BIOTECHNOLOGY QUALITY CONTROL, vol. 38, no. 9, 1 September 2004 (2004-09-01), pages 1 - 32, XP055731017 (B1)

BEWLEY MARIA C ET AL: "X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32", BIOCHEMISTRY,, vol. 38, no. 8, 23 February 1999 (1999-02-23), pages 2535 - 2541, XP002508535, ISSN: 0006-2960, [retrieved on 19990202], DOI: 10.1021/BI9824543 (B1)

BOERNER ET AL: "Defining Your Product Profile and Maintaining Control Over It Part 3", BIOPROCESS TECHNICAL, 1 October 2005 (2005-10-01), pages 51 - 56, XP055731022, Retrieved from the Internet <URL:https://www.bioprocessintl.com/process-monitoring-and-controls/defining-your-product-profile-and-maintaining-control-over-it-part-3-product-related-impurities> [retrieved on 20200916] (B1)

CARNICER MARC ET AL: "Macromolecular and elemental composition analysis and extracellular metabolite balances of Pichia pastoris growing at different oxygen levels", MICROBIAL CELL FACTORIES, SPRINGER, vol. 8, no. 1, 9 December 2009 (2009-12-09), pages 65, XP021067674, ISSN: 1475-2859 (B1)

J. AHN ET AL: "BiopharmaLynx: A new bioinformatics tool for automated LC/MS peptide mapping assignment", WATERS - THE SCIENCE OF WHAT IS POSSIBLE, 1 September 2008 (2008-09-01), pages 1 - 6, XP055731028, Retrieved from the Internet <URL:https://www.waters.com/webassets/cms/library/docs/720002754en.pdf> [retrieved on 20200916] (B1)

K. KITAMOTO ET AL: "Genetic Engineering of a Sake Yeast Producing No Urea by Successive Disruption of Arginase Gene", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 57, 1 January 1991 (1991-01-01), pages 301 - 306, XP055731032, DOI: 10.1128/AEM.57.1.301-306.1991 (B1)

M. M. HARMSEN ET AL: "Properties, production, and applications of camelid single-domain antibody fragments", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 77, no. 1, 18 August 2007 (2007-08-18), Berlin/Heidelberg, pages 13 - 22, XP055519503, ISSN: 0175-7598, DOI: 10.1007/s00253-007-1142-2 (B1)

MIDDELHOVEN ET AL: "The pathway of arginine breakdown in Saccharomyces cerevisiae", BIOCHIMICA ET BIOPHYSICA ACTA, ELSEVIER, AMSTERDAM, NL, vol. 93, no. 3, 9 December 1964 (1964-12-09), pages 650 - 652, XP025792842, ISSN: 0304-4165, [retrieved on 19641209], DOI: 10.1016/0304-4165(64)90349-6 (B1)

O. BOUÉ ET AL: "Production and biochemical characterization of the recombinant Boophilus microplus Bm95 antigen from Pichia pastoris", EXPERIMENTAL AND APPLIED ACAROLOGY, vol. 32, no. 1-2, 1 January 2004 (2004-01-01), pages 119 - 128, XP055731099 (B1)

PAUL RAINVILLE ET AL: "Detecting Carbamylation of Intact Proteins and Peptides by LC/MS(/MS)", WATERS, 1 January 2002 (2002-01-01), pages 1, XP055731108, Retrieved from the Internet <URL:https://www.waters.com/webassets/cms/library/docs/wa20706.pdf> [retrieved on 20200916] (B1)

PINGZUO LI ET AL: "Expression of Recombinant Proteins in Pichia Pastoris", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 142, 1 January 2007 (2007-01-01), New York, pages 105 - 124, XP055220800, ISSN: 0273-2289, DOI: 10.1007/s12010-007-0003-x (B1)

RAHBARIZADEH F ET AL: "High expression and purification of the recombinant camelid anti-MUC1 single domain antibodies in Escherichia coli", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, vol. 44, no. 1, 1 November 2005 (2005-11-01), pages 32 - 38, XP027390195, ISSN: 1046-5928, [retrieved on 20050930], DOI: 10.1016/J.PEP.2005.04.008 (B1)

RAHBARIZADEH F ET AL: "Over expression of anti-MUC1 single-domain antibody fragments in the yeast Pichia pastoris", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 43, no. 5, 1 February 2006 (2006-02-01), pages 426 - 435, XP025037145, ISSN: 0161-5890, [retrieved on 20060201], DOI: 10.1016/J.MOLIMM.2005.03.003 (B1)

STEINLEIN L M ET AL: "Production and purification of N-terminal half-transferrin in Pichia pastoris.", PROTEIN EXPRESSION AND PURIFICATION OCT 1995, vol. 6, no. 5, October 1995 (1995-10-01), pages 619 - 624, ISSN: 1046-5928 (B1)

STEINLEIN L M ET AL: "Production and purification of N-terminal half-transferrin in Pichia pastoris.", PROTEIN EXPRESSION AND PURIFICATION, vol. 6, October 1995 (1995-10-01), pages 619 - 624 (B1)

WO-A1-2006/030220 (B1)

WO-A2-2008/142164 (B1)

ZHANG WENHUI ET AL: "Rational design and optimization of fed-batch and continuous fermentations.", METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.) 2007, vol. 389, 2007, pages 43 - 64, ISSN: 1064-3745 (B1)

"THE METABOLISM AND MOLECULAR PHYSIOLOGY OF SACCHAROMYCES CEREVISIAE, 2nd ed.", 1 January 2004, CRC PRESS, article J. RICHARD DICKINSON: "Chapter 4 - Nitrogen metabolism", pages: 104 - 113, XP055750936 (B1)