paragraph 1 page 2185, column 2, paragraph 1 page 2189, paragraph 32 page 2193, paragraph 67, CHENG ALBERT W ET AL: "Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system", October 2013 (2013-10), CELL RESEARCH, VOL.

23, NR.10, PAGE(S) 1163-1171, XP002735688, ISSN: 1001-0602(print) the whole document, PRASHANT MALI ET AL: "CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering", NATURE BIOTECHNOLOGY, vol.31, no.

9, 1 August 2013 (2013-08-01) , pages 833-838, XP055149275, ISSN: 1087-0156, DOI:

10.1038/nbt.2675, MAEDER MORGAN L ET AL: "CRISPR RNA-guided activation of endogenous human genes", NATURE METHODS, vol.10, no.10, October 2013 (2013-10), pages 977-979+2pp, XP002736341, ISSN: 1548-7091, GILBERT J R ET AL: "A novel short hairpin RNA (shRNA) expression system promotes Sox9-dependent gene silencing", PLASMID, NEW YORK,NY, US, vol.62, no.1, 1 July 2009 (2009-07-01), pages 50-55, XP026145060, ISSN: 0147-619X, DOI: 10.1016/J.PLASMID.2009.04.001 [retrieved on 2009-04-21]

Enclosed is a translation of the patent claims in Norwegian. Please note that as per the Norwegian Patents Acts, section 66i the patent will receive protection in Norway only as far as there is agreement between the translation and the language of the application/patent granted at the EPO. In matters concerning the validity of the patent, language of the application/patent granted at the EPO will be used as the basis for the decision. The patent documents published by the EPO are available through Espacenet (http://worldwide.espacenet.com) or via the search engine on our website here: https://search.patentstyret.no/