DUPUY F P ET AL: "Lentiviral transduction of human hematopoietic cells by HIV-1- and SIV-based vectors containing a bicistronic cassette driven by various internal promoters", THE JOURNAL OF GENE MEDICINE, vol. 7, no. 9, 1 September 2005 (2005-09-01), pages 1158-1171, XP055166269, ISSN: 1099-498X, DOI: 10.1002/jgm.769 (B1)

Zufferey at at., 1999. Journal of Virology, Vol. 73 No. 4. pp 2886-2892, Apr 1999 (B2)

MITTA B ET AL: "Advanced modular self-inactivating lentiviral expression vectors for multigene interventions in mammalian cells and in vivo transduction", NUCLEIC ACIDS RESEARCH, INFORMATION RETRIEVAL LTD, vol. 30, no. 21, 1 November 2002 (2002-11-01), page e113, XP002321925, ISSN: 0305-1048, DOI: 10.1093/NAR/GNF112 (B1)

RAMEZANI A ET AL: "Lentiviral vectors for enhanced gene expression in human hematopoietic cells", MOLECULAR THERAPY, NATURE PUBLISHING GROUP, GB, vol. 2, no. 5, 1 November 2000 (2000-11-01), pages 458-469, XP002307687, ISSN: 1525-0016, DOI: 10.1006/MTHE.2000.0190 (B1)

REAL G ET AL: "Improvement of lentiviral transfer vectors using cis-acting regulatory elements for increased gene expression", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 91, no. 6, 15 June 2011 (2011-06-15), pages 1581-1591, XP019943607, ISSN: 1432-0614, DOI: 10.1007/S00253-011-3392-2 (B1)

SALMON P ET AL: "High-Level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 96, no. 10, 15 November 2000 (2000-11-15), pages 3392-3398, XP002951290, ISSN: 0006-4971 (B1)

WO-A2-2012/170911 (B1)

ZANTA-BOUSSIF M A ET AL: "Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: application to the gene therapy of WAS", GENE THERAPY, vol. 16, no. 5, 1 May 2009 (2009-05-01), pages 605-619, XP055166280, ISSN: 0969-7128, DOI: 10.1038/gt.2009.3 (B1)

15 Jun 2011, Real et al., 2011. Appl Microbiol Biotechnol, Vol.91, pp 1581-1591 (B2)

Dupuy et al., 2005, J Gene Medicine, Vol. 7 No. 9, pp 1158-1171, 09 May 2005 (B2)

Durand and Cimarelli, 2011, Viruses. Vol. 3, pp 132-159, 14 Feb 2011 (B2)

Johnston el al., 2013, Gene Therapy, Vol. 20, pp 607-615,20 Sep 2012 (B2)

Liechtenstein T., 2013. Cancers. Vol. 5. pp 815-837,02 Jul 2013 (B2)

Mitta et al., 2002, Nucleic Acids Research, Vol. 30 No. 21, el13,2002 (B2)

Mitzushima and Nagata, Nucleic Acids Research, Vol. 18 No17, p 5322, 1990 (B2)

Ramezani et al., 2000. Molecular Therapy, Vol. 2 No. 5, pp458-469, 23 Oct 2000 (B2)

Salmon P. al., 2000. High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors, Blood, Vol.96 No. 10. pp 3392-3398,15 Nov 2005 (B2)

Schambach el al., 2013, Human Gene Therapy?. Vol 24. pp132-142 (B2)

Schambach, et al. Improving Transcriptional Termination ofSelf-Inactivating Gamma-retroviral and Lentiviral Vectors, 2007,Molecular Therapy. VoL 15 No, 6.1167-1173, 03 Apr 2007 (B2)

Schamback et al., 2006, Gene Therapy, Vol. 13. pp 641 -64515 Dec 2005 (B2)

Serafini et al., 2004, Haematologica, Vol. 89. pp 86-95Jan 2004 (B2)

US-B1- 6 284 469 (B2)

Zanta-Boussif et al., 2009, Gene Therapy, Vol. 16. pp 605-619,05 Mar 2009 (B2)

JOHNSTON J M ET AL: "Generation of an optimized lentiviral vector encoding a high-expression factor VIII transgene for gene therapy of hemophilia A", GENE THERAPY, vol. 20, no. 6, 1 June 2013 (2013-06-01), pages 607-615, XP055166279, ISSN: 0969-7128, DOI: 10.1038/gt.2012.76 (B1)