CHRISTIAN DELVARE ET AL: "Efficient Three-Step One-Pot Synthesis of a Novel 2,3,5-Substituted Pyrazine Library", ACS COMBINATORIAL SCIENCE, vol. 13, no. 5, 12 September 2011 (2011-09-12), pages 449-452, XP055157727, ISSN: 2156-8952, DOI: 10.1021/co200062n (B1)

YONGJUN MAO ET AL: "Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, no. 11, 1 June 2013 (2013-06-01), pages 3090-3104, XP0055183165, ISSN: 0968-0896, DOI: 10.1016/j.bmc.2013.03.053 (B1)

EP-A1- 1 518 855 (B1)

EP-A1- 2 428 508 (B1)

GARY PHILLIPS ET AL: "Design, Synthesis, and Activity of 2,6-Diphenoxypyridine-Derived Factor Xa Inhibitors", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 44, no. 10, 20 May 1999 (1999-05-20), pages 1349-1355, XP002595442, ISSN: 0022-2623, DOI: 10.1021/JM980667K [retrieved on 1999-04-24] (B1)

US-A1- 2007 049 578 (B1)

US-A1- 2010 216 793 (B1)

WO-A1-2008/009458 (B1)

WO-A1-2009/051822 (B1)

WO-A1-2009/145856 (B1)

WO-A1-2009/158571 (B1)

WO-A1-2010/144647 (B1)

WO-A1-2012/135801 (B1)

WO-A1-2012/171337 (B1)

WO-A1-2013/014448 (B1)

WO-A1-2013/030665 (B1)

WO-A1-2013/060098 (B1)

WO-A1-2013/108754 (B1)

WO-A1-2013/144180 (B1)

WO-A2-2009/131687 (B1)

WO-A2-2012/170976 (B1)

EP-A1- 1 184 376 (B1)