BOYD ROBERT S ET AL: "The effect of botulinum neurotoxins on the release of insulin from the insulinoma cell lines HIT-15 and RINm5F", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, US, vol. 270, no. 31, 1 January 1995 (1995-01-01), pages 18216-18218, XP001010301, ISSN: 0021-9258 (B1)

FORAN P ET AL: "Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release.", BIOCHEMISTRY 27 FEB 1996, vol. 35, no. 8, 27 February 1996 (1996-02-27), pages 2630-2636, XP002531828, ISSN: 0006-2960 (B1)

JONES ET AL: "Development of improved SNAP25 endopeptidase immuno-assays for botulinum type A and E toxins", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 329, no. 1-2, 23 October 2007 (2007-10-23), pages 92-101, XP022389333, ISSN: 0022-1759 (B1)

MARCONI S ET AL: "A protein chip membrane-capture assay for botulinum neurotoxin activity", TOXICOLOGY AND APPLIED PHARMACOLOGY, ACADEMIC PRESS, vol. 233, no. 3, 15 December 2008 (2008-12-15), pages 439-446, XP025678926, ISSN: 0041-008X [retrieved on 2008-09-19] (B1)

NABOKINA S ET AL: "Intracellular location of SNAP-25 in human neutrophils.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 20 OCT 1997, vol. 239, no. 2, 20 October 1997 (1997-10-20), pages 592-597, XP002531826, ISSN: 0006-291X (B1)

WO-A1-95/33850 (B1)

SCHULTE-BAUKLOH HEINRICH ET AL: "Persistence of the synaptosomal-associated protein-25 cleavage product after intradetrusor botulinum toxin A injections in patients with myelomeningocele showing an inadequate response to treatment.", BJU INTERNATIONAL NOV 2007, vol. 100, no. 5, November 2007 (2007-11), pages 1075-1080, XP002531827, ISSN: 1464-4096 (B1)

SHIMAZAKI Y ET AL: "Phosphorylation of 25-kDa synaptosome-associated protein. Possible involvement in protein kinase C-mediated regulation of neurotransmitter release.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 14 JUN 1996, vol. 271, no. 24, 14 June 1996 (1996-06-14), pages 14548-14553, XP002531829, ISSN: 0021-9258 (B1)

US-A1- 2008 064 054 (B1)

WILLIAMSON L C ET AL: "Clostridial neurotoxins and substrate proteolysis in intact neurons: botulinum neurotoxin C acts on synaptosomal-associated protein of 25 kDa.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 29 MAR 1996, vol. 271, no. 13, 29 March 1996 (1996-03-29), pages 7694-7699, XP002531830, ISSN: 0021-9258 (B1)

WO-A-2006/042149 (B1)

RASOOLY REUVEN ET AL: "Development of an in vitro activity assay as an alternative to the mouse bioassay for Clostridium botulinum neurotoxin type A.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY JUL 2008, vol. 74, no. 14, July 2008 (2008-07), pages 4309-4313, XP002531831, ISSN: 1098-5336 (B1)