AUBRY JACQUES: "MAB 8B6 ANTI-O-ACETYL GD2 GANGLIOSIDE", HYBRIDOMA, LIEBERT, NEW YORK, NY, US, vol. 16, no. 6, 1 January 1997 (1997-01-01), page 568, XP008078553, ISSN: 0272-457X (B1)

WO-A2-2011/070214 (B1)

BESSARD ANNE ET AL: "High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer", MOLECULAR CANCER THERAPEUTICS, vol. 8, no. 9, 1 September 2009 (2009-09-01), pages 2736-2745, XP002664481, ISSN: 1535-7163 (B1)

DUBOIS SIGRID ET AL: "Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8(+)/CD44(high) T cells and its antitumor action", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 180, no. 4, 1 February 2008 (2008-02-01), pages 2099-2106, XP002636845, ISSN: 0022-1767 (B1)

ELIZABETH ORTIZ-SÁNCHEZ ET AL: "Antibody cytokine fusion proteins: applications in cancer therapy", EXPERT OPINION ON BIOLOGICAL THERAPY, ASHLEY, LONDON, GB, vol. 8, no. 5, 1 May 2008 (2008-05-01), pages 609-632, XP008145785, ISSN: 1471-2598, DOI: 10.1517/14712598.8.5.609 (B1)

EP-A1- 1 777 294 (B1)

KASPAR MANUELA ET AL: "The antibody-mediated targeted delivery of interleukin-15 and GM-CSF to the tumor neovasculature inhibits tumor growth and metastasis", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 67, no. 10, 1 May 2007 (2007-05-01), pages 4940-4948, XP002468217, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-07-0283 (B1)

KERMER VANESSA ET AL: "An antibody fusion protein for cancer immunotherapy mimicking IL-15 trans-presentation at the tumor site.", MOLECULAR CANCER THERAPEUTICS JUN 2012 LNKD- PUBMED:22491823, vol. 11, no. 6, June 2012 (2012-06), pages 1279-1288, XP002683666, ISSN: 1538-8514 (B1)

MORTIER ERWAN ET AL: "Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC, US, vol. 281, no. 3, 20 January 2006 (2006-01-20), pages 1612-1619, XP002394330, ISSN: 0021-9258, DOI: 10.1074/JBC.M508624200 (B1)

PENICHET MANUEL L ET AL: "Antibody-cytokine fusion proteins for the therapy of cancer", JOURNAL OF IMMUNOLOGICAL METHODS, vol. 248, no. 1-2, 1 February 2001 (2001-02-01), pages 91-101, XP002664486, ISSN: 0022-1759 (B1)

RONCA ROBERTO ET AL: "Delivering cytokines at tumor site: The immunocytokine-conjugated anti-EDB-fibronectin antibody case", IMMUNOBIOLOGY, vol. 214, no. 9-10, Sp. Iss. SI, September 2009 (2009-09), pages 800-810, XP002664483, ISSN: 0171-2985 (B1)

SINGH HARJEET ET AL: "Combining adoptive cellular and immunocytokine therapies to improve treatment of B-lineage malignancy", CANCER RESEARCH, vol. 67, no. 6, March 2007 (2007-03), pages 2872-2880, XP002664485, ISSN: 0008-5472 (B1)

US-A- 5 736 137 (B1)

VINCENT MARIE ET AL: "Development of two IL15 immunocytokines targeting either GD2-or CD20-tumoral bearing cells", CYTOKINE, vol. 56, no. 1, Sp. Iss. SI, 8 September 2011 (2011-09-08), page 102, XP002664482, & 9TH JOINT MEETING OF THE INTERNATIONAL-CYTOKINE-SOCIETY/INTERNATION AL SOCIETY-FOR-INTERFERON-AND-CYT; FLORENCE, ITALY; OCTOBER 09 -12, 2011 ISSN: 1096-0023, DOI: 10.1016/j.cyto.2011.07.396 IRN - ISSN 1 (B1)

Vanessa Kermer et al: "Antibody fusion proteins for cancer immunotherapy mimicking iL-15 trans presentation at the tumor site", CIMT Cancer Immunotherapy 8th annual meeting abstractbook 2010 CIMT abstractbook 2010, 26 May 2010 (2010-05-26), pages 1-171, XP002683665, Retrieved from the Internet: URL:http://meeting.cimt.eu/cimt-meeting/fi les/dl/CIMT_Abstractbook_2010.pdf [retrieved on 2012-09-13] (B1)

WEI X Q ET AL: "The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 167, no. 1, 1 July 2001 (2001-07-01), pages 277-282, XP002394329, ISSN: 0022-1767 (B1)

WO-A1-2008/043777 (B1)

WO-A1-2009/135031 (B1)

WO-A2-2007/001677 (B1)

WO-A2-2009/002562 (B1)

BESSARD ANNE ET AL: "High antitumor activity of RLI, an IL15-IL15Ralpha fusion protein, in metastatic melanoma and colorectal cancer", CYTOKINE, vol. 48, no. 1-2, Sp. Iss. SI, October 2009 (2009-10), page 105, XP002664484, & TRI-SOCIETY ANNUAL CONFERENCE OF THE INTERNATIONAL-CYTOKINE-SOCIETY/I NTERNATIONAL-SOCIETY-OF-INTERFE; LISBON, PORTUGAL; OCTOBER 17 -21, 2009 ISSN: 1043-4666 (B1)