Beskrivelse
2012 (2012-02), XP002677737, Retrieved from the Internet:
URL:http://www.avonex.com/pdfs/guides/Avos tartgrip_IFU.pdf [retrieved on 2012-06-13], HURWITZ B J ET AL: "Tolerability and safety profile of 12- to 28-week treatment with interferon beta-1b 250 and 500 @?g QOD in patients with relapsing-remitting multiple sclerosis: A multicenter, randomized, double-blind, parallel-group pilot study", CLINICAL THERAPEUTICS, EXCERPTA MEDICA, PRINCETON, NJ, US, vol. 30, no.6, 1 June 2008 (2008-06-01), pages 1102-1112, XP022938732, ISSN: 0149-2918, DOI: 10.1016/J.CLINTHERA.2008.06.013 [retrieved on 2008-06-01], WROE: "Effects of dose titration on tolerability and efficacy of interferon beta-1b in people with multiple sclerosis.", JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, vol.33, no.3, 1 January 2005 (2005-01-01), pages 309-318, XP55029629, ISSN: 0300-0605, BRANDES D W ET AL: "Alleviating flu-like symptoms with dose titration and analgesics in MS patients on intramuscular interferon beta-1a therapy: A pilot study", CURRENT MEDICAL RESEARCH AND OPINION, INFORMA HEALTHCARE, GB, vol.23, no.7, 1 July 2007 (2007-07-01), pages 1667-1672, XP009160129, ISSN: 0300-7995, DOI:
10.1185/030079907X210741, MATSON M A ET AL: "Dose titration of intramuscular interferon beta-1a reduces the severity and incidence of flu-like symptoms during treatment initiation", CURRENT MEDICAL RESEARCH AND OPINION, INFORMA HEALTHCARE, GB, vol.27, no.
12, 1 December 2011 (2011-12-01), pages 2271-2278, XP009160128, ISSN: 0300-7995, DOI: 10.1185/03007995.2011.630720, Anon.: "Betaferon", , 8 February 2010 (2010-02-08), XP002677736, Retrieved from the Internet: URL:http://www.pharmaline.co.il/images/new sletterregistration/bayer/betaferondoctor. pdf [retrieved on 2012-06-13]
Enclosed is a translation of the patent claims in Norwegian. Please note that as per the Norwegian Patents Acts, section 66i the patent will receive protection in Norway only as far as there is agreement between the translation and the language of the application/patent granted at the EPO. In matters concerning the validity of the patent, language of the application/patent granted at the EPO will be used as the basis for the decision. The patent documents published by the EPO are available through Espacenet (http://worldwide.espacenet.com) or via the search engine on our website here: https://search.patentstyret.no/
Krav
IPC-klasse
Fullmektig i Norge:
Fullmektig i EP:
2011.03.15, US 201161452807 P
2011.04.19, US 201161476930 P
Anon.: "Betaferon", , 8 February 2010 (2010-02-08), XP002677736, Retrieved from the Internet: URL:http://www.pharmaline.co.il/images/new sletterregistration/bayer/betaferondoctor. pdf [retrieved on 2012-06-13] (B1)
Anon.: "Instructions for use: Avostartgrip Titration Kit", Biogen Idec Inc. , February 2012 (2012-02), XP002677737, Retrieved from the Internet: URL:http://www.avonex.com/pdfs/guides/Avos tartgrip_IFU.pdf [retrieved on 2012-06-13] (B1)
Anon.: "Medication Guide Appendix: Instructions for Preparing and Giving a Dose with an Avonex Prefilled Syringe", Biogen Idec Inc. , August 2010 (2010-08), XP002677734, Retrieved from the Internet: URL:http://www.avonex.com/pdfs/guides/Liqu id_appendix_I61023.pdf [retrieved on 2012-06-13] (B1)
BRANDES D W ET AL: "Alleviating flu-like symptoms with dose titration and analgesics in MS patients on intramuscular interferon beta-1a therapy: A pilot study", CURRENT MEDICAL RESEARCH AND OPINION, INFORMA HEALTHCARE, GB, vol. 23, no. 7, 1 July 2007 (2007-07-01), pages 1667-1672, XP009160129, ISSN: 0300-7995, DOI: 10.1185/030079907X210741 (B1)
WROE: "Effects of dose titration on tolerability and efficacy of interferon beta-1b in people with multiple sclerosis.", JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, vol. 33, no. 3, 1 January 2005 (2005-01-01), pages 309-318, XP55029629, ISSN: 0300-0605 (B1)
HURWITZ B J ET AL: "Tolerability and safety profile of 12- to 28-week treatment with interferon beta-1b 250 and 500 @?g QOD in patients with relapsing-remitting multiple sclerosis: A multicenter, randomized, double-blind, parallel-group pilot study", CLINICAL THERAPEUTICS, EXCERPTA MEDICA, PRINCETON, NJ, US, vol. 30, no. 6, 1 June 2008 (2008-06-01), pages 1102-1112, XP022938732, ISSN: 0149-2918, DOI: 10.1016/J.CLINTHERA.2008.06.013 [retrieved on 2008-06-01] (B1)
J PHILLIPS ET AL: "A multicenter, open-label, phase II study of the immunogenicity and safety of a new prefilled syringe (liquid) formulation of avonex in patients with multiple sclerosis", CLINICAL THERAPEUTICS, vol. 26, no. 4, 1 April 2004 (2004-04-01), pages 511-521, XP55029619, ISSN: 0149-2918, DOI: 10.1016/S0149-2918(04)90053-7 (B1)
MATSON M A ET AL: "Dose titration of intramuscular interferon beta-1a reduces the severity and incidence of flu-like symptoms during treatment initiation", CURRENT MEDICAL RESEARCH AND OPINION, INFORMA HEALTHCARE, GB, vol. 27, no. 12, 1 December 2011 (2011-12-01), pages 2271-2278, XP009160128, ISSN: 0300-7995, DOI: 10.1185/03007995.2011.630720 (B1)
Rice G P A; Ebers G C; Lublin F D; Knobler R L: "Ibuprofen treatment versus gradual introduction of interferon beta-1b in patients with MS", Neurology Neurology, vol. 52, no. 9 1 June 1999 (1999-06-01), pages 1893-1895, XP002677735, DOI: 10.1212/WNL.52.9.1893 Retrieved from the Internet: URL:http://www.neurology.org/content/52/9/ 1893.full [retrieved on 2012-06-12] (B1)
FROHMAN ELLIOT ET AL: "Disease-modifying therapy in multiple sclerosis: strategies for optimizing management", NEUROLOGIST, WLLIAMS AND WILKINS, BALTIMORE, MD, US, vol. 8, no. 4, 1 July 2002 (2002-07-01), pages 227-236, XP009160126, ISSN: 1074-7931 (B1)
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