CA-A1- 2 759 146 (B1)

HORTON HOLLY M ET AL: "Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 116, no. 16, 4 October 2010 (2010-10-04), pages 3004-3012, XP009146207, ISSN: 0006-4971, DOI: 10.1182/BLOOD-2010-01-265280 (B1)

PRESTA ET AL: "Engineering of therapeutic antibodies to minimize immunogenicity and optimize function", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER BV, AMSTERDAM, NL, vol. 58, no. 5-6, 7 August 2006 (2006-08-07), pages 640-656, XP005611419, ISSN: 0169-409X, DOI: 10.1016/J.ADDR.2006.01.026 (B1)

XIAN-LIANG LI ET AL: "Promises and Obstacles for the Blockade of CD40-CD40L Interactions in Allotransplantation", TRANSPLANTATION, vol. 86, no. 1, 1 July 2008 (2008-07-01), pages 10-15, XP55018800, ISSN: 0041-1337, DOI: 10.1097/TP.0b013e31817c4b97 (B1)

WILLIAM R STROHL: "Optimization of Fc-mediated effector functions of monoclonal antibodies", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, vol. 20, no. 6, 1 December 2009 (2009-12-01), pages 685-691, XP002631328, ISSN: 0958-1669, DOI: 10.1016/J.COPBIO.2009.10.011 [retrieved on 2009-11-04] (B1)

WO-A1-2008/150494 (B1)

SIBERIL ET AL: "FcgammaR: The key to optimize therapeutic antibodies?", CRITICAL REVIEWS IN ONCOLOGY / HEMATOLOGY, ELSEVIER SCIENCE IRELAND LTD., LIMERICK, IE, vol. 62, no. 1, 7 March 2007 (2007-03-07), pages 26-33, XP005912443, ISSN: 1040-8428, DOI: 10.1016/J.CRITREVONC.2006.12.003 (B1)