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Fullmektig i Norge:
Org.nummer: 986406263
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Fullmektig i EP:
2009.06.25, US 220480 P
2010.01.07, US 293087 P
Alan D. Borthwick ET AL: "Design and Synthesis of Pyrrolidine-5,5- trans- lactams (5-Oxohexahydropyrrolo[3,2- b ]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 2. Potency and Chirality", Journal of Medicinal Chemistry, vol. 45, no. 1, 1 January 2002 (2002-01-01), pages 1-18, XP055217624, ISSN: 0022-2623, DOI: 10.1021/jm0102203 (B1)
Rautio J: et al Prodrugs; design and clinical applications; Nature Reviews, 2008, 7,. pages .255-270 (B2)
COLLINS M A ET AL: "Novel pyrrole-containing progesterone receptor modulators", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 14, 1 January 2004 (2004-01-01), pages 2185-2189, XP002347318, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2004.02.054 (B1)
DE-A1- 4 439 493 (B1)
DE-B- 1 070 760 (B1)
DEZI: 'Modeling of 5-HT2A and 5-HT2C Receptors and of Their Complexes with Actual and Potential Antipsychotic Drugs' PHD THESIS, POMPEU FABRA UNIVERSITY 2007, BARCELONA, pages 1 - 239, XP008143584 (B1)
EP-A1- 0 339 976 (B1)
EP-A1- 0 409 435 (B1)
EP-A2- 0 367 141 (B1)
Frank G. M. Niele ET AL: "Palladium(II) cage compounds based on diphenylglycoluril", Journal of the American Chemical Society, vol. 110, no. 1, 1 January 1988 (1988-01-01), pages 172-177, XP055217436, ISSN: 0002-7863, DOI: 10.1021/ja00209a027 (B1)
Frank G. M. Niele ET AL: "Rhodium(III) cage compounds based on diphenylglycoluril", Journal of the American Chemical Society, vol. 111, no. 6, 1 March 1989 (1989-03-01) , pages 2078-2085, XP055217434, ISSN: 0002-7863, DOI: 10.1021/ja00188a022 (B1)
Hans Bundgaard: "N-hydroxymethyl derivatives; N-acyloxyalkyl derivatives", Design of prodrugs, 1 January 1985 (1985-01-01), pages 16-24, XP055218148, Amsterdam, New York, Oxford ISBN: 978-0-44-480675-8 Retrieved from the Internet: URL:- [retrieved on 2015-10-05] (B1)
Hans Bundgard: 1 January 1985 (1985-01-01) (B1)
Hiroshi Hongo ET AL: "Preparation of optically active photopyridone by lipase-catalysed asymmetric resolution?1", Journal of the Chemical Society, Perkin Transactions 1, no. 11, 1 January 1997 (1997-01-01), pages 1747-1754, XP055217539, ISSN: 0300-922X, DOI: 10.1039/a605698i (B1)
J T Link ET AL: "Regiosektive Imide Reduction : An Issue Staurosporine in the Total Synthesis of staurosporine", Tetrahedron letters, vol. 35, no. 49, 1 January 1994 (1994-01-01), pages 9135-9138, XP055217443, (B1)
J. T. Link ET AL: "First Total Synthesis of Staurosporine and ent-Staurosporine", Journal of the American Chemical Society, vol. 117, no. 1, 1 January 1995 (1995-01-01), pages 552-553, XP055217525, ISSN: 0002-7863, DOI: 10.1021/ja00106a072 (B1)
Jinzhen Lin ET AL: "Diazonamide Support Studies: Stereoselective Formation of the C10 Chiral Center in both the CDEFG and AEFG Fragments", Organic Letters, vol. 10, no. 18, 18 September 2008 (2008-09-18), pages 3969-3972, XP055217651, ISSN: 1523-7060, DOI: 10.1021/ol8014336 (B1)
LOZHKIN ET AL: "The first conglomerate in the series of 2,4,6,8,10-pentaazatricyclo[5.3.1.0<3.11>] undecane-1,5-diones", MENDELEEV COMMUNICATIONS, INSTITUTE OF PHYSICS PUBLISHING, BRISTOL, GB, vol. 17, no. 2, 5 April 2007 (2007-04-05), pages 85-87, XP022022625, ISSN: 0959-9436 (B1)
MIAO ET AL: 'Characterization of a Novel Metabolite Intermediate of Ziprasidone in Hepatic Cytosolic Fractions of Rat, Dog, and Human by ESI-MS/MS, Hydrogen/Deuterium Exchange, and Chemical Derivatization' DRUG METABOLISM AND DISPOSITION vol. 33, no. 7, 2005, pages 879 - 883, XP008149118 (B1)
PASS M ET AL: "Thrombin inhibitors based on [5,5] trans-fused indane lactams", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 9, no. 12, 21 June 1999 (1999-06-21), pages 1657-1662, XP004167734, ISSN: 0960-894X, DOI: 10.1016/S0960-894X(99)00244-9 (B1)
Richard H. Hutchings ET AL: "An Oxazoline-Mediated Synthesis of the Pyrrolophenanthridine Alkaloids and Some Novel Derivatives", The Journal of Organic Chemistry, vol. 61, no. 3, 1 January 1996 (1996-01-01), pages 1004-1013, XP055217535, ISSN: 0022-3263, DOI: 10.1021/jo951474x (B1)
Shozo Yamada: "Oxidation Products of Hydroxylycoctonam", Bulletin of the Chemical Society of Japan, vol. 35, no. 4, 1 January 1962 (1962-01-01), pages 670-672, XP055217429, ISSN: 0009-2673, DOI: 10.1246/bcsj.35.670 (B1)
Takashi Mizutani ET AL: "Discovery of Novel Benzoxazinones as Potent and Orally Active Long Chain Fatty Acid Elongase 6 Inhibitors", Journal of Medicinal Chemistry, vol. 52, no. 22, 26 November 2009 (2009-11-26), pages 7289-7300, XP055217712, ISSN: 0022-2623, DOI: 10.1021/jm900915x (B1)
US-A- 3 573 308 (B1)
US-A- 4 831 031 (B1)
US-A1- 2007 031 513 (B1)
US-A1- 2009 068 290 (B1)
US-A1- 2009 143 403 (B1)
US-B1- 6 444 668 (B1)
WO-A1-00/66571 (B1)
WO-A1-2004/026864 (B1)
WO-A1-2005/019215 (B1)
WO-A1-2005/090357 (B1)
WO-A1-2007/082907 (B1)
WO-A1-2010/149755 (B1)
WO-A1-2011/161030 (B1)
WO-A1-97/36893 (B1)
WO-A1-98/49157 (B1)
WO-A2-2006/090273 (B1)
WO-A2-2007/084391 (B1)
YATES N D ET AL: "1,3-Dipolar cycloadditions to oxidopyraziniums", HETEROCYCLES : AN INTERNATIONAL JOURNAL FOR REVIEWS AND COMMUNICATIONS IN HETEROCYCLIC CHEMISTRY, JAPAN INSTITUTE OF HETEROCYCLIC CHEMISTRY, JP, vol. 40, no. 1, 1 January 1995 (1995-01-01), pages 331-347, XP009186581, ISSN: 0385-5414 (B1)
YODA ET AL: 'Sml2-mediated hetero-coupling reaction of lactams with aldehydes; synthesis of indolizidine alkaloids, (-)-delta-coniceine, (+)-5-epiindolizidine 167B and (+)-lentiginosine' TETRAHEDRON LETTERS vol. 42, no. 13, 2001, pages 2509 - 2512, XP004232284 (B1)
Bristol Meyers Squibb information leaflet about Abilify (B2)
J. T. Link ET AL: "Staurosporine and ent -Staurosporine: The First Total Syntheses, Prospects for a Regioselective Approach, and Activity Profiles 1", Journal of the American Chemical Society, vol. 118, no. 12, 1 January 1996 (1996-01-01), pages 2825-2842, XP055217532, ISSN: 0002-7863, DOI: 10.1021/ja952907g (B2)
Pitman, I.H, Pro-Drugs of Amides, Imides and Amines, Medicinal Research Reviews; 1981; 1(2), pages 189-214 (B2)
Prescribing information about Aristrada (B2)
Andrew Fensome ET AL: "Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro -1 H -indol-5-yl)-1-methyl-1 H -pyrrole-2-carbonitrile (WAY-255348)", Journal of Medicinal Chemistry, vol. 51, no. 6, 1 March 2008 (2008-03-01), pages 1861-1873, XP055217649, ISSN: 0022-2623, DOI: 10.1021/jm701080t (B1)
Statushistorie
Hovedstatus | Beslutningsdato, detaljstatus |
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EP patent gjort gjeldende i Norge | Patent endret etter innsigelse i EPO |
EP patent gjort gjeldende i Norge | Venter på oversettelse av endret patent etter innsigelse (B2) i EPO |
EP patent gjort gjeldende i Norge | EP patent besluttet gjeldende i Norge |
EP under behandling | Forespørsel om å gjøre EP patent gyldig er mottatt |
Korrespondanse
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Journal beskrivelse
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Innkommende
EP Publiseringsdokument fra EPO
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Innkommende, AR525296083
Korrespondanse (Hovedbrev inn)
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Innkommende
EP Publiseringsdokument fra EPO
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Innkommende
EP Publiseringsdokument fra EPO
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Innkommende
EP Publiseringsdokument fra EPO
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Innkommende
EP Publiseringsdokument fra EPO
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Utgående
EP Registreringsbrev (3210)
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Innkommende
Søknadsskjema Patent
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Innkommende
EP Publiseringsdokument fra EPO
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Til betaling:
Betalingshistorikk:
Beskrivelse / Fakturanummer | Betalingsdato | Beløp | Betaler | Status |
---|---|---|---|---|
Årsavgift 15. avg. år (EP) | 2024.06.27 | 6310 | COMPUTER PACKAGES INC. | Betalt og godkjent |
Årsavgift 14. avg. år (EP) | 2023.06.28 | 4500 | COMPUTER PACKAGES INC. | Betalt og godkjent |
32216713 expand_more expand_less | 2022.12.29 | 5500 | PLOUGMANN VINGTOFT NUF | Betalt |
Opprettholdelse av EP-patent etter innsigelse (B2)
5500 = 1 X 5500
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Årsavgift 13. avg. år (EP) | 2022.06.29 | 4200 | COMPUTER PACKAGES INC. | Betalt og godkjent |
Årsavgift 12. avg. år (EP) | 2021.06.29 | 3850 | COMPUTER PACKAGES INC. | Betalt og godkjent |
Årsavgift 11. avg. år (EP) | 2020.06.29 | 3500 | COMPUTER PACKAGES INC. | Betalt og godkjent |
Årsavgift 10. avg. år (EP) | 2019.06.27 | 3200 | COMPUTER PACKAGES INC. | Betalt og godkjent |
Årsavgift 9. avg. år (EP) | 2018.06.28 | 2850 | COMPUTER PACKAGES INC | Betalt og godkjent |
31715312 expand_more expand_less | 2017.10.13 | 5500 | Plougmann Vingtoft | Betalt |
Valideringsgebyr EP-patent
5500 = 1 X 5500
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Årsavgift 8. avg. år (EP) | 2017.06.28 | 2550 | Computer Packages Inc | Betalt og godkjent |