BOLOTIN E M ET AL: "AMMONIUM SULFATE GRADIENTS FOR EFFICIENT AND STABLE REMOTE LOADING OF AMPHIPATHIC WEAK BASES INTO LIPOSOMES AND LIGANDOLIPOSOMES", JOURNAL OF LIPOSOME RESEARCH, vol. 4, no. 1, 1 January 1994 (1994-01-01) , pages 455-479, XP000572717, TAYLOR & FRANCIS, PHILADELPHIA, PA, US ISSN: 0898-2104 (B1)

FormuMax Scientific Inc.: "Doxoves - Liposome Doxorubicin Compared to Doxil", Doxoves-Liposomal Doxorubicin , 17 November 1995 (1995-11-17), pages 1-4, XP002684032, Retrieved from the Internet: URL:www.liposomeexpert.com/categories/Drug -Loaded-Liposomes [retrieved on 2012-09-24] (B1)

HARAN G ET AL: "Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases", BIOCHIMICA ET BIOPHYSICA ACTA. BIOMEMBRANES, vol. 1151, no. 2, 19 September 1993 (1993-09-19), pages 201-215, XP023352276, AMSTERDAM, NL ISSN: 0005-2736, DOI: 10.1016/0005-2736(93)90105-9 [retrieved on 1993-09-19] (B1)

JP-T- 2005 509 000 (B1)

WO-A1-2008/080367 (B1)

MARY ANN JORDAN, ET AL.: 'The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth' MOLECULAR CANCER THERAPEUTICS vol. 4, no. 7, July 2005, pages 1086 - 1095 (B1)

TATIANA OKOUNEVA, ET AL.: 'Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase' MOLECULAR CANCER THERAPEUTICS vol. 7, no. 7, July 2008, pages 2003 - 2011, XP008152621 (B1)

WANG Y., ET AL.: 'Eribulin Mesilate. Antimitotic drug, Tubulin polymerization inhibitor, Oncolytic' DRUGS OF THE FUTURE vol. 32, no. 8, 2007, pages 681 - 698 (B1)

JP-T- 2006 513 189 (B1)