FOSTER A B: "Deuterium isotope effects in the metabolism of drugs and xenobiotics: implications for drug design", ADVANCES IN DRUG RESEARCH, ACADEMIC PRESS, LONDON, GB, vol. 14, 1 January 1985 (1985-01-01), pages 1-40, XP009086953, ISSN: 0065-2490 (B1)

MILLER ET AL: "Therapeutic use of dextromethorphan: Key learnings from treatment of pseudobulbar affect", JOURNAL OF NEUROLOGICAL SCIENCES, ELSEVIER SCIENTIFIC PUBLISHING CO, AMSTERDAM, NL, vol. 259, no. 1-2, 19 July 2007 (2007-07-19), pages 67-73, XP022149385, ISSN: 0022-510X, DOI: 10.1016/J.JNS.2006.06.030 (B1)

NAHAS Z ET AL: "Rapid response of emotional incontinence to selective serotonin reuptake inhibitors", JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCE, AMERICAN PSYCHIATRIC PRESS, WASHINGTON, DC, US, vol. 10, no. 4, 1 October 1998 (1998-10-01), pages 453-455, XP009131261, ISSN: 0895-0172 (B1)

RICHTER G ET AL: "Synthesis of deuterated dextromethorphan derivatives", ARKIVOC : FREE ONLINE JOURNAL OF ORGANIC CHEMISTRY, vol. 2008, no. 3, 1 March 2008 (2008-03-01), pages 182-193, XP002490643, ISSN: 1551-7012 (B1)

WO-A2-2008/097924 (B1)

SELIGER G M ET AL: "Fluoxetine improves emotional incontinence", BRAIN INJURY, TAYLOR AND FRANCIS, LONDON, GB, vol. 6, no. 3, 1 May 1992 (1992-05-01), pages 267-270, XP009131264, ISSN: 0269-9052, DOI: 10.3109/02699059209029668 (B1)

TAN I ET AL: "Emotional incontinence: a dramatic response to paroxetine", AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, ROYAL AUSTRALASIAN COLLEGE OF PHYSICIANS, AU, vol. 26, no. 6, 1 December 1996 (1996-12-01), page 844, XP009131263, ISSN: 0004-8291 (B1)

WO-A1-2008/137474 (B1)

SCHIFFER RANDOLPH ET AL: "Review of pseudobulbar affect including a novel and potential therapy", JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCE, AMERICAN PSYCHIATRIC PRESS, WASHINGTON, DC, US, vol. 17, no. 4, 1 January 2005 (2005-01-01), pages 447-454, XP009131259, ISSN: 0895-0172, DOI: 10.1176/APPI.NEUROPSYCH.17.4.447 (B1)