BODNAR RICHARD J: "CHAPTER 20: Preclinical Effects of Opioid Antagonists on Feeding and Appetite", OPIATE RECEPTORS AND ANTAGONISTS: FROM BENCH TO CLINIC, DEAN, REGINALD L.; BILSKY, EDWARD J.; NEGUS, S. STEVENS (EDS.), HUMANA PRESS, 1 January 2009 (2009-01-01), pages 387-406, XP009177015, ISBN: 978-1-58829-881-2 (B1)

FOR THE COR-I STUDY GROUP ET AL: "Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial", THE LANCET, LANCET LIMITED. LONDON, GB, vol. 376, no. 9741, 21 August 2010 (2010-08-21), pages 595-605, XP027598237, ISSN: 0140-6736, DOI: 10.1016/S0140-6736(10)60888-4 [retrieved on 2010-08-21] (B1)

IGOR ELMAN ET AL: "Food Intake and Reward Mechanisms in Patients with Schizophrenia: Implications for Metabolic Disturbances and Treatment with Second-Generation Antipsychotic Agents", NEUROPSYCHOPHARMACOLOGY, 15 March 2006 (2006-03-15), XP055108736, ISSN: 0893-133X, DOI: 10.1038/sj.npp.1301051 (B1)

TODTENKOPF M S ET AL: "In vivo characterization of novel, peripherally-acting opioid antagonists", SOCIETY FOR NEUROSCIENCE ABSTRACT VIEWER AND ITINERARY PLANNER, vol. 38, 2008, XP009177016, & 38TH ANNUAL MEETING OF THE SOCIETY-FOR-NEUROSCIENCE; WASHINGTON, DC, USA; NOVEMBER 15 -19, 2008 (B1)

TODTENKOPF M S; O'NEILL K S; KELLY S M; RICHIE K A; DEAN R L III; DAHM J; DEAVER D R: "The novel opioid receptor modulator RDC-0313 (ALKS 33) reduces olanzapine-induced weight gain in female rats", ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE, vol. 40, 1 January 2010 (2010-01-01), page 630.3, XP055108391, US ISSN: 0190-5295 (B1)

ZHANG J ET AL: "The mu-opioid receptor subtype is required for the anorectic effect of an opioid receptor antagonist", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE, NL, vol. 545, no. 2-3, 18 September 2006 (2006-09-18), pages 147-152, XP028029212, ISSN: 0014-2999, DOI: 10.1016/J.EJPHAR.2006.06.069 [retrieved on 2006-09-18] (B1)

US-A1- 2008 004 324 (B1)

WENTLAND M P ET AL: "Syntheses and opioid receptor binding properties of carboxamido-substituted opioids", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 19, no. 1, 1 January 2009 (2009-01-01), pages 203-208, XP025816907, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2008.10.134 [retrieved on 2008-11-07] (B1)

WO-A1-2006/052710 (B1)

WO-A2-2007/067714 (B1)

YUAN CHUN-SU ET AL: "Methylnaltrexone potentiates body weight and fat reduction with leptin", JOURNAL OF OPIOID MANAGEMENT: A MEDICAL JOURNAL OF PROPER AND ADEQUATE USE, WESTON MEDICAL PUBLISHING, LLC, US, vol. 5, no. 6, 1 November 2009 (2009-11-01), pages 373-378, XP009177014, ISSN: 1551-7489 (B1)

US-A1- 2004 254 208 (B1)